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Verospiron 25mg Tablet
Verospiron/Spironolactone is a diuretic (water pill) primarily used for the treatment of heart failure, high blood pressure, and conditions causing swelling (edema). It is also prescribed to address low potassium levels in the body (hypokalemia).
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✅ Description:
- Verospiron is a long-acting aldosterone antagonist.
- Acts through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule.
- Causes increased excretion of sodium and water while retaining potassium and magnesium.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Verospiron.
Pregnancy
CONSULT YOUR DOCTOR
Verospiron may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Verospiron is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CAUTION
Verospiron may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
Verospiron should be used with caution in patients with kidney disease. A dose adjustment of Verospiron may be needed. Please consult your doctor. Use of Verospiron is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Verospiron in patients with liver disease. Please consult your doctor.
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✔️ Uses of Verospiron 25mg Tablet
- Heart failure
- High blood pressure (hypertension)
- Edema (swelling) caused by various conditions
- Treatment of low potassium levels in the body (hypokalemia)
✔️ How does Verospiron 25mg Tablet work?
Verospiron is a potassium-sparing diuretic that lowers blood pressure and reduces swelling by eliminating excess water and electrolytes without causing potassium loss.
✔️ Side Effects of Verospiron 25mg Tablet
Nausea, Vomiting, Leg cramps, Dizziness, Drowsiness, Confusion, Breast enlargement in males, Increased creatinine level in blood.
✔️ Quick Suggestions:
- May cause dizziness initially; avoid activities requiring concentration.
- May increase potassium levels; avoid potassium supplements and potassium-rich foods.
- Regularly monitor kidney function, potassium levels, and blood pressure.
- Report dizziness, diarrhea, vomiting, swelling in feet, or difficulty breathing to the doctor.
✔️ Indication
Hypertension, Edema, Hypokalemia, Hepatic cirrhosis with ascites and edema, Hyperaldosteronism, Severe congestive heart failure.
✔️ Pharmacology
- Spironolactone, the active ingredient, is a specific pharmacologic antagonist of aldosterone.
- Acts by binding to receptors at the aldosterone-dependent sodium-potassium exchange site.
- Causes increased sodium and water excretion while retaining potassium.
✔️ Dosage & Administration:
- Varied dosages based on the specific condition being treated.
- Adjustments may be made according to the patient's response.
- Regular monitoring of kidney function and potassium levels is essential.
- Should be taken with food. Taking it early in the day can reduce the need to wake up at night for frequent urination.
✔️ Interaction
- ACE inhibitors: Concomitant use may lead to severe hyperkalemia.
- Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur.
- Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur.
- Lithium: High risk of lithium toxicity.
- Digoxin: Verospiron increases the half-life of digoxin.
✔️ Contraindications
Anuria, Hyperkalemia, Acute or progressive renal insufficiency, Addison's disease.
✔️ Pregnancy & Lactation
Use in pregnancy and lactation requires careful consideration of potential benefits versus risks.
✔️ Precautions & Warnings
- Patients with kidney problems or difficulty urinating should use Verospiron with caution.
- Lifestyle changes like exercise and a low-salt diet may enhance its effectiveness.
- Avoid alcohol consumption.
- Inform the doctor about kidney, liver, or heart diseases, pregnancy, or other medications being used.
- Pregnant or breastfeeding women should consult their doctor.
✔️ Storage Conditions
- Store in a cool and dry place protected from light.
- Keep out of reach of children.
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