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Triben DS 400mg Tablet 10pcs
Albendazole 400mg is an antiparasitic medication. It works by keeping the worms from absorbing sugar (glucose), thereby depleting their energy level. This causes the worms to die and treats your infection.
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✅ Description:
Triben DS is indicated in single and mixed infestations of:
- Hookworm (Ancylostoma, Necator)
- Roundworm (Ascaris)
- Threadworm (Enterobius)
- Whipworm (Trichuris)
- Strongyloides
- Tapeworm
- Opisthorchi
- Hydatid.
Safety Advices
Alcohol
UNSAFE
It is not known whether it is safe to consume alcohol with Triben DS. Consult your doctor for advice.
Pregnancy
UNSAFE
Triben DS may be unsafe to use during pregnancy. Limited human studies suggest potential harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing it. Consult your doctor for guidance.
Breastfeeding
CONSULT YOUR DOCTOR
Triben DS is considered safe during breastfeeding. Human studies indicate that the drug does not pass into breast milk significantly and is not harmful to the baby. Ensure it is prescribed by a healthcare professional.
Driving
CAUTION
Triben DS may reduce alertness, affect vision, and cause drowsiness and dizziness. It is unsafe to drive if you experience these symptoms.
Kidney
CONSULT YOUR DOCTOR
Triben DS is likely safe to use in patients with kidney disease. Limited data suggests that dose adjustment may not be necessary. Consult your doctor for guidance.
Liver
CONSULT YOUR DOCTOR
Triben DS should be used with caution in patients with liver disease. Dose adjustment may be necessary, and you should inform your doctor if you experience signs of jaundice. Consult your doctor for advice.
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✔️ Pharmacology:
- Albendazole, the active ingredient in Triben DS, is a wide-range anthelmintic.
- It exhibits vermicidal, ovicidal, and larvicidal activities.
- Albendazole blocks glucose uptake in vulnerable helminths, leading to energy depletion and eventual immobilization and death.
- It inhibits parasite tubulin polymerization, contributing to its anthelmintic effect.
- Albendazole is metabolized in the liver, poorly absorbed from the gastrointestinal tract, and excreted in urine.
✔️ Dosage and Administration of Triben DS:
For Adults & Children over 2 years:
- 400 mg (1 tablet or 10 ml suspension) as a single dose for various infections.
- For strongyloidiasis or taeniasis, 400 mg (1 tablet or 10 ml suspension) daily for 3 consecutive days. For Children of 1-2 years:
- The recommended dose is a single dosage of 200 mg (5 ml suspension). For Children below 1 year:
- Not recommended. For Hydatid disease (Echinococcosis):
- Albendazole dosage varies based on body weight and the type of echinococcosis.
- Cycles of treatment are repeated after specific intervals.
✔️ Interaction of Triben DS:
- No interactions involving Albendazole, either pharmacodynamic or pharmacokinetic, have been reported.
✔️ Contraindications:
- Neonates: Not commonly used.
- Children: Dose reduction may be indicated in children weighing less than 10 kg.
- Pregnant women: Avoid during pregnancy.
- Concurrent infection: No evidence to suggest dosage adjustment in renal, hepatic, or cardiac failure.
✔️ Side Effects of Triben DS:
- Gastrointestinal disturbances, headache, dizziness, changes in liver enzymes, reversible alopecia (rare), rash, fever, blood disorders including leucopenia and pancytopenia.
- Allergic reactions, including anaphylactic shock in case of cyst rupture.
- Shaking and meningism in cerebral disease.
✔️ Pregnancy & Lactation:
- US FDA Pregnancy category of Albendazole is C.
- Albendazole should be avoided in pregnancy and lactation unless potential benefits outweigh possible risks to the fetus.
✔️ Precautions & Warnings:
- Blood checks and liver function tests before treatment and twice during each cycle.
- Caution in breastfeeding.
- Exclude pregnancy before starting treatment.
- Use in Echinococcosis under constant medical supervision with regular monitoring of liver function and blood counts.
✔️ Storage Conditions
Keep in a dry put, absent from light and warm. Keep out of the reach of children.
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