Cefaclav 500mg Tablet (Cefuroxime Axetil 500mg + Clavulanic Acid 125mg) is a combination medicine used to treat bacterial infections, such as pharyngitis, sinusitis, and urinary tract infections.
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Cefaclav 500mg Tablet is a combination medication containing Cefuroxime and Clavulanic Acid, which belong to the antibiotic and beta-lactamase inhibitor groups, respectively. It is used to treat various bacterial infections, including pharyngitis, tonsillitis, otitis media, sinusitis, respiratory tract infections, skin and skin structure infections, urinary tract infections, bone and joint infections, gonorrhea, Lyme disease, septicemia, meningitis, switch therapy after surgery.
Before taking Cefaclav 500mg Tablet, it is important to inform your doctor about any history of colitis, liver problems, or kidney problems. Caution should be exercised in patients with a known sensitivity to penicillin. The use of Cefaclav 500mg Tablet should be approached with caution during pregnancy, and it is generally not recommended for breastfeeding women.
It is important to note that Cefaclav 500mg Tablet is not suitable for children under the age of three months. The most commonly reported side effects of this medication include nausea, vomiting, diarrhea, and abdominal discomfort or pain. If any of these side effects worsen or do not improve, it is advisable to consult your doctor for advice.
It is crucial to follow your doctor's instructions regarding the dosage and duration of treatment with Cefaclav 500mg Tablet and to complete the full course of medication as prescribed. If you have any concerns or questions about the medication or its side effects, it is best to consult with your doctor or healthcare provider for guidance.
Consuming alcohol with Cefaclav 500mg Tablet does not cause any harmful side effects.
Cefaclav 500mg Tablet is generally regarded as safe to use during pregnancy. Animal studies have shown minimal or no adverse effects on the developing fetus.
It is safe to use Cefaclav 500mg Tablet while breastfeeding, as human studies, indicates that the drug is not significantly excreted into breastmilk and poses no harm to the nursing infant.
Consult with your doctor before taking Cefaclav 500mg Tablet if you have kidney disease, as there is limited information available on its use in such patients.
There is limited information available on the use of Cefaclav 500mg Tablet in patients with liver disease. Please consult your doctor.
Cefaclav 500mg Tablet contains clavulanic acid and cefuroxime. Cefuroxime is an antibiotic that prevents bacteria from developing a protective layer that is necessary for their survival. A beta-lactamase inhibitor known as clavulanic acid increases the antibacterial effectiveness of cefuroxime by decreasing resistance.
If you miss a dose of Cefaclav 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Cefaclav 500mg Tablet is used for the treatment of various bacterial infections such as:
Cefuroxime is an antibiotic belonging to the second-generation cephalosporin class. It is effective against a wide range of bacteria, including those that produce beta-lactamase enzymes. Cefuroxime works by disrupting the process of cell wall formation in bacteria, ultimately leading to their death.
Clavulanic acid, derived from Streptomyces clavuligerus, is a natural compound that acts as a beta-lactamase inhibitor. It has a similar structure to beta-lactam antibiotics and binds irreversibly to beta-lactamase enzymes, which are responsible for breaking down certain antibiotics. By inhibiting beta-lactamase enzymes, clavulanic acid protects cefuroxime from degradation, allowing it to remain effective against bacteria that produce these enzymes. This combination of cefuroxime and clavulanic acid provides an effective treatment option for bacterial infections.
For adolescents and adults (13 years and older), the recommended dosage of Cefaclav 500mg Tablet for various conditions is as follows:
For pediatric patients (3 months to 12 years), the recommended dosage of Cefaclav 500mg Tablet 4's for various conditions is as follows:
The Cefaclav 500mg Tablet can be taken with or without food, as it does not need to be taken with regard to meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. However, it is always a good practice to follow the instructions provided by your doctor or the specific instructions on the medication packaging.
Cefaclav 500mg Tablet may interact with several medications, including:
Antacids such as esomeprazole and omeprazole: These medications can reduce the absorption of cefuroxime, so it is recommended to take them at least 2 hours before or after taking Cefaclav 500mg Tablet.
Anticoagulants like warfarin: Cefuroxime may enhance the effects of anticoagulants, increasing the risk of bleeding. Close monitoring of blood clotting parameters is advisable when these medications are used together.
Anti-gout medication like probenecid: Probenecid may increase the concentration of cefuroxime in the blood by reducing its elimination. Your doctor may need to adjust the dosage of Cefaclav 500mg Tablet in such cases.
Diuretics like furosemide: Cefuroxime can enhance the nephrotoxic effects of diuretics. Close monitoring of kidney function is recommended when these medications are used together.
Oral contraceptives containing estrogen and progesterone: Cefuroxime may reduce the effectiveness of oral contraceptives. It is advisable to use alternative methods of contraception while taking Cefaclav 500mg Tablet.
Cefuroxime-Clavulanic Acid, the combination present in Cefaclav 500mg Tablet, should not be used by individuals with a known allergy to cephalosporin antibiotics or those who have a history of pseudomembranous colitis. It is important to inform your doctor about any allergies you may have before starting this medication. Additionally, if you have a history of pseudomembranous colitis, which is a severe inflammation of the colon, it is not recommended to take this medication. Your doctor will consider your medical history and assess the suitability of alternative treatment options for you.
Antibiotics should be avoided if at all possible throughout the first trimester. Cefuroxime-Clavulanic Acid, on the other hand, can be safely used to treat urinary and other infections later in pregnancy. Cefuroxime-Clavulanic Acid is excreted in modest amounts in breast milk. However, the possibility of the newborn being sensitized should be considered.
Store in a cool, dry place (below 30o C), away from light and moisture. Keep out of the reach of children.
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