Cefaclav 500mg Tablet 4pcs

Uses of Cefaclav 500mg Tablet

• Treatment of Bacterial infections

How does Cefaclav 500mg Tablet work?

Cefaclav 500mg Tablet contains clavulanic acid and cefuroxime. Cefuroxime is an antibiotic that prevents bacteria from developing a protective layer that is necessary for their survival. A beta-lactamase inhibitor known as clavulanic acid increases the antibacterial effectiveness of cefuroxime by decreasing resistance.

What If you forget to take Cefaclav 500mg TabletABLET?

If you miss a dose of Cefaclav 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side Effects of Cefaclav 500mg Tablet

• Diarrhea
• Headache
• Difficult or painful urination
• Change in taste
• Abdominal pain
• Acid or sour stomach

Quick Suggestions:

• To effectively treat bacterial infections, it is important to follow the prescribed course of Cefaclav 500mg Tablet as instructed by your doctor. Do not skip any doses and complete the full treatment even if you start feeling better. Prematurely stopping the medication can result in the infection recurring and becoming more difficult to treat.
• Take Cefaclav 500mg Tablet with food to avoid potential stomach upset. It is possible to experience diarrhea as a side effect, and taking probiotics may help alleviate this symptom. If you notice bloody stools or develop abdominal cramps, it is important to inform your doctor.
• If you experience an itchy rash, swelling of the face, throat, or tongue, or difficulty breathing while taking Cefaclav 500mg Tablet, discontinue its use immediately and seek medical attention.
• Do not use any leftover medication to treat future infections. Always consult your doctor before taking any antibiotic.
• Tobacco usage should be avoided.
• It is advisable to refrain from alcohol consumption while undergoing treatment with Cefaclav 500mg Tablet.

Indication of Cefaclav 500mg Tablet

Cefaclav 500mg Tablet is used for the treatment of various bacterial infections such as:

• Pharyngitis and/or tonsillitis
• Acute bacterial otitis media
• Acute bacterial maxillary sinusitis
• Lower respiratory tract infections including pneumonia
• Acute bacterial exacerbations of chronic bronchitis and secondary bacterial infections of acute bronchitis
• Skin and skin structure infections
• Urinary tract infections
• Bone and joint infections
• Gonorrhoea (uncomplicated and disseminated gonococcal infections)
• Early Lyme disease (erythema migrans)
• Septicemia
• Meningitis
• Switch therapy (injectable to oral) after surgery when the patient’s condition is improved

Pharmacology

Cefuroxime is an antibiotic belonging to the second-generation cephalosporin class. It is effective against a wide range of bacteria, including those that produce beta-lactamase enzymes. Cefuroxime works by disrupting the process of cell wall formation in bacteria, ultimately leading to their death.

Clavulanic acid, derived from Streptomyces clavuligerus, is a natural compound that acts as a beta-lactamase inhibitor. It has a similar structure to beta-lactam antibiotics and binds irreversibly to beta-lactamase enzymes, which are responsible for breaking down certain antibiotics. By inhibiting beta-lactamase enzymes, clavulanic acid protects cefuroxime from degradation, allowing it to remain effective against bacteria that produce these enzymes. This combination of cefuroxime and clavulanic acid provides an effective treatment option for bacterial infections.

Dosage & Administration of Cefaclav 500mg Tablet

For adolescents and adults (13 years and older), the recommended dosage of Cefaclav 500mg Tablet for various conditions is as follows:

• Pharyngitis/tonsillitis: Take 250 mg twice daily for 5-10 days.
• Acute bacterial maxillary sinusitis: Take 250 mg twice daily for 10 days.
• Acute bacterial exacerbation of chronic bronchitis: Take 250-500 mg twice daily for 10 days.
• Secondary bacterial infections of acute bronchitis: Take 250-500 mg twice daily for 5-10 days.
• Uncomplicated skin and skin structure infections: Take 250-500 mg twice daily for 10 days.
• Uncomplicated urinary tract infections: Take 250 mg twice daily for 7-10 days.
• Uncomplicated Gonorrhoea: Take 1000 mg twice daily as a single dose.
• Community-acquired pneumonia: Take 250-500 mg twice daily for 5-10 days.
• MDR Typhoid Fever: Take 500 mg twice daily for 10-14 days.
• Early Lyme disease: Take 500 mg twice daily for 20 days.

For pediatric patients (3 months to 12 years), the recommended dosage of Cefaclav 500mg Tablet 4's for various conditions is as follows:

• Pharyngitis/tonsillitis: Take 20 mg/kg/day divided into two doses for 5-10 days.
• Acute otitis media: Take 30 mg/kg/day divided into two doses for 10 days.
• Acute bacterial maxillary sinusitis: Take 30 mg/kg/day divided into two doses for 10 days.
• Impetigo: Take 30 mg/kg/day divided into two doses for 10 days.

The Cefaclav 500mg Tablet can be taken with or without food, as it does not need to be taken with regard to meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine. However, it is always a good practice to follow the instructions provided by your doctor or the specific instructions on the medication packaging.

Interaction

Cefaclav 500mg Tablet may interact with several medications, including:

Antacids such as esomeprazole and omeprazole: These medications can reduce the absorption of cefuroxime, so it is recommended to take them at least 2 hours before or after taking Cefaclav 500mg Tablet.

Anticoagulants like warfarin: Cefuroxime may enhance the effects of anticoagulants, increasing the risk of bleeding. Close monitoring of blood clotting parameters is advisable when these medications are used together.

Anti-gout medication like probenecid: Probenecid may increase the concentration of cefuroxime in the blood by reducing its elimination. Your doctor may need to adjust the dosage of Cefaclav 500mg Tablet in such cases.

Diuretics like furosemide: Cefuroxime can enhance the nephrotoxic effects of diuretics. Close monitoring of kidney function is recommended when these medications are used together.

Oral contraceptives containing estrogen and progesterone: Cefuroxime may reduce the effectiveness of oral contraceptives. It is advisable to use alternative methods of contraception while taking Cefaclav 500mg Tablet.

Contraindications

Cefuroxime-Clavulanic Acid, the combination present in Cefaclav 500mg Tablet, should not be used by individuals with a known allergy to cephalosporin antibiotics or those who have a history of pseudomembranous colitis. It is important to inform your doctor about any allergies you may have before starting this medication. Additionally, if you have a history of pseudomembranous colitis, which is a severe inflammation of the colon, it is not recommended to take this medication. Your doctor will consider your medical history and assess the suitability of alternative treatment options for you.

Pregnancy & Lactation

Antibiotics should be avoided if at all possible throughout the first trimester. Cefuroxime-Clavulanic Acid, on the other hand, can be safely used to treat urinary and other infections later in pregnancy. Cefuroxime-Clavulanic Acid is excreted in modest amounts in breast milk. However, the possibility of the newborn being sensitized should be considered.

Precautions & Warnings

• Before starting Cefaclav 500mg Tablet, it is important to inform your doctor if you have any allergies, particularly against antibiotics, as well as any kidney or liver problems. Self-medication withCefaclav 500mg Tablet should be avoided, as it may contribute to antibiotic resistance, where antibiotics become ineffective against specific bacterial infections. Therefore, it is crucial to consult your doctor before taking this medication.
• If you have colitis, which is inflammation of the colon, it is advisable to consult your doctor before taking Cefaclav 500mg Tablet. Additionally, if you are receiving concurrent treatment with potent diuretics, caution should be exercised, and it is recommended to consult your doctor.
• If you are pregnant or planning to become pregnant, it is important to consult your doctor before taking Cefaclav 500mg Tablet to assess its suitability for your situation. Furthermore, if you are breastfeeding, it is advisable to avoid taking Cefaclav 500mg Tablet, as it may pass into breast milk and potentially affect the nursing infant.
• Alcohol consumption should be avoided while taking Cefaclav 500mg Tablet to prevent potential unpleasant side effects or interactions with the medication. It is always best to follow your doctor's instructions and guidance regarding the use of Cefaclav 500mg Tablets and to address any concerns or questions you may have with them.

Storage Conditions

Store in a cool, dry place (below 30o C), away from light and moisture. Keep out of the reach of children.