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Afix 200mg 7pcs Capsules

Generic: Cefixime

Type: Capsule

Pack Size: 7pcs

Cefixime is a semisynthetic third-generation cephalosporin that kills bacteria by disrupting the synthesis of their cell walls. It is stable against beta-lactamase enzymes, which makes it effective against resistant bacteria. Its absorption is approximately 40%-50%, irrespective of food intake.

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✅ Description:

Afix (Cefixime) is a third-generation cephalosporin antibiotic with bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. It is used to treat the following infections caused by susceptible microorganisms:

Upper Respiratory Tract Infections (URTI):

  • Includes conditions like otitis media or other URTI, especially when resistant bacteria or significant treatment failure risks are suspected.

Lower Respiratory Tract Infections (LRTI):

  • Includes bronchitis.

Urinary Tract Infections (UTI):

  • Includes conditions like cystitis, cystourethritis, and pyelonephritis.

Pathogens Treated:

  • Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Klebsiella species, Haemophilus influenzae (beta-lactamase positive/negative), Moraxella catarrhalis (beta-lactamase positive/negative), and Enterobacter species.

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✔️ Afix 200: Side Effects

Gastrointestinal:

  • Diarrhea, stool changes (more common with higher doses), nausea, abdominal pain, dyspepsia, vomiting, flatulence, and rarely pseudomembranous colitis.

Central Nervous System:

  • Headache and dizziness.

Hypersensitivity Reactions:

  • Rash, pruritus, urticaria, drug fever, arthralgia (typically resolves upon discontinuation).

Hematological:

  • Rare cases of thrombocytopenia, leukopenia, and eosinophilia.

Miscellaneous:

  • Genital pruritus and vaginitis.
✔️ Dosage and Administration of Afix 200
  • Treatment duration: Typically 7 days but may extend up to 14 days if necessary.
  • Food: Absorption is not significantly affected by food.

Dosage:

  • Adults and Children Over 10 Years: 200–400 mg daily as a single dose or divided into two doses, depending on the severity of the infection.
  • Elderly: Same as adult dosage. Dosage adjustments may be necessary for severe renal impairment.
  • Children (6 months–10 years): 8 mg/kg/day as a single or divided dose. Suggested daily suspension doses:
    • 6 months to 1 year: 3.75 mL
    • 1–4 years: 5 mL
    • 5–10 years: 10 mL
  • Typhoid Fever: 5 mg/kg body weight twice daily for 10–14 days.
  • Children Over 50 kg or Older than 10 Years: Use adult dosage.
  • Children Under 6 Months: Safety and efficacy not established.

Renal Impairment:

  • If creatinine clearance is ≥20 mL/min: Normal dose.
  • If creatinine clearance <20 mL/min: Do not exceed 200 mg once daily.
✔️ Drug Interactions
  • Gastric lavage may be considered. No specific antidote is available.
  • Cefixime is not significantly removed by hemodialysis or peritoneal dialysis.
✔️ Drug Interactions
  • Cephalosporins, including Cefixime, may prolong prothrombin time. Caution is advised in patients on anticoagulants.
✔️ Contraindications
  • Known hypersensitivity to cephalosporins or any component of the medication.
✔️ Use in Pregnancy and Lactation
  • Pregnancy: No adequate studies are available. Should only be used if needed.
  • Lactation: It is unknown if Cefixime is excreted in human milk. Use with caution in nursing mothers.
✔️ Precautions and Warnings

Allergy Risk:

  • Exercise caution in patients with penicillin allergies, as cross-reactivity between penicillins and cephalosporins is possible.
  • Discontinue immediately if an allergic reaction occurs.

Renal Impairment:

  • Monitor renal function closely and adjust dosage as necessary.

Antibiotic-Associated Diarrhea:

  • Broad-spectrum antibiotics may disrupt normal gut flora, potentially leading to Clostridium difficile-associated diarrhea.
✔️ Storage Conditions
  • Store below 30°C, protected from light and moisture.
  • Keep out of reach of children.
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Delivery typically takes 1-2 business days, depending on your location.

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Currently, ePharma only delivers within Bangladesh.

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We accept debit/credit cards, Bkash, Nagad, and cash on delivery.

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Check our pricing section for Afix 200mg 7pcs Capsules price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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