Cef-3 Forte Powder for Suspension 50ml

Uses of Cef-3 Forte Powder for Suspension

• Treatment of Bacterial infections

How does Cef-3 Forte Powder for Suspension work?

Cef-3 Forte Powder for Suspension is a powerful antibiotic with bacteriostatic properties. It kills the susceptible bacteria by blocking bacterial cell wall synthesis. Unlike other cephalosporins, it can also remain unaffected by the toxic proteins produced by the bacteria (such as beta-lactamases). Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication, and reduce the severity of the infection.

Side Effects of Cef-3 Forte Powder for Suspension

• Stomach pain
• Dark or clay-colored stools
• Dizziness
• Excessive air or gas in the stomach
• Heartburn
• Chest pain
• Headache
• Fever
• Diarrhea
• Itching or skin rash
• Vaginal discharge
• Headache
• Yellowing of the skin or eyes (jaundice)
• Acid or sour stomach

Quick Suggestions:

• It is important to follow your doctor's prescription of Cef-3 Forte Powder for Suspension to effectively treat your infection and alleviate your symptoms. Make sure not to skip any doses and complete the full course of treatment, even if you start feeling better. Prematurely stopping the medication may result in a more difficult-to-treat infection.
• To prevent an upset stomach, take the oral suspension with food.
• While taking Cef-3 Forte Powder for Suspension, you may experience diarrhea as a side effect. However, this should subside once you finish the prescribed course. If the diarrhea persists or if you notice blood in your stools, notify your doctor.
• If you develop a rash, itchy skin, swelling of the face and mouth, or have difficulty breathing, discontinue the use of Cef-3 Forte Powder for Suspension immediately and seek medical attention. These could be signs of an allergic reaction.
• After completing the full course of Cef-3 Forte Powder for Suspension (50 ml), it is advisable to take probiotics to restore healthy bacteria in the intestines that may have been affected by the antibiotic. Probiotics can help reduce the risk of antibiotic-associated diarrhea. Foods like yogurt, cheese, sauerkraut, kombucha, and kimchi are examples of fermented foods that can aid in replenishing good intestinal bacteria.
• Including fiber-rich foods in your diet can also help stimulate the growth of healthy gut bacteria. Whole grains such as whole-grain bread and brown rice are recommended for this purpose.
• It is best to avoid excessive intake of calcium and iron-enriched foods and beverages while taking Cef-3 Forte Powder for Suspension, as they may interfere with its effectiveness.
• Lastly, it is advisable to avoid consuming alcoholic beverages while taking Cef-3 Forte Powder for Suspension, as alcohol can lead to dehydration and disrupt your sleep. This can hinder your body's ability to fight off infections with the help of medication.

Indication

Cef-3 Forte Powder for Suspension belongs to the class of antibiotics known as cephalosporins. It is used to treat infections of the ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia), and urinary system (cystitis and kidney infections) caused by sensitive organisms (bacteria). In addition, it is used to treat uncomplicated gonorrhea (cervical/urethral). 

Pharmacology

Cefixime is an oral antibiotic that belongs to the group of semisynthetic third-generation cephalosporins. It is effective in killing a broad spectrum of bacteria, both gram-positive and gram-negative, at plasma concentrations that can be easily achieved. Cefixime acts by disrupting the production of the bacterial cell wall, resulting in bacterial cell death. It demonstrates strong stability in the presence of the beta-lactamase enzyme, making it effective against organisms that are resistant to penicillins and certain cephalosporins due to the presence of beta-lactamases.

When taken orally, Cefixime is absorbed into the body at a rate of approximately 40% to 50%, regardless of whether it is taken with or without meals.

Dosage & Administration of Cef-3 Forte Powder for Suspension

The standard duration of treatment with Cefixime is 7 days, although it can be extended up to 14 days depending on the severity of the infection.

For adults and children over 12 years of age, the recommended dose is 200-400 mg (1 to 2 capsules) per day. This can be taken as a single dose or divided into two doses. In the case of uncomplicated cervical/urethral gonococcal infections, a single oral dose of 400 mg is typically recommended.

For children aged 6 months and older, the usual dose is 8 mg/kg/day, given as a single dose or divided into two doses. Alternatively, the following dosage guidelines can be followed:

• ½-1 year: 75 mg daily
• 1-4 years: 100 mg daily
• 5-10 years: 200 mg daily
• 11-12 years: 300 mg daily

In the treatment of typhoid fever, the recommended dosage is 10 mg/kg/day for a duration of 14 days.

It is important to note that the safety and effectiveness of Cefixime have not been established in children under 6 months of age.

Administration:

• Follow your physician's instructions for administering Cef-3 Forte Powder for Suspension to your child. It can be taken with or without food.
• Before use, shake the bottle thoroughly to loosen the dry powder. Add the sterile water provided with the package up to the indicated mark on the bottle. Adjust the volume as needed by adding additional water. Close the bottle tightly and shake the mixture well.
• The specific quantity (ml) to be given to your child will be determined by your doctor. Even if your child's symptoms improve, do not discontinue treatment with Cef-3 Forte Powder for Suspension. It is important to complete the recommended duration of therapy as advised by your doctor to effectively control the infection.

Interaction

Cef-3 Forte Powder for Suspension can potentially interact with certain vaccines such as BCG, cholera vaccine, and typhoid vaccine. It may also interact with anticoagulant medications like warfarin and anticonvulsant medications such as carbamazepine.

In addition, Cef-3 Forte Powder for Suspensionmay have interactions with certain disease conditions. These include colitis, which is inflammation of the inner lining of the colon, renal dysfunction (impaired kidney function), liver disease, and seizure disorders.

It is important to inform your doctor about any vaccines, medications, or existing health conditions your child may have before starting Cef-3 Forte Powder for Suspension to ensure safe and effective use of the medication. Your doctor can provide guidance on any necessary precautions or adjustments to the treatment plan.

Contraindications

Cefixime is an oral semisynthetic third-generation cephalosporin antibiotic. It is bactericidal against a wide spectrum of gram-positive and gram-negative pathogens at easily obtained plasma concentrations. It kills germs by interfering with the development of the bacterial cell wall. It is particularly stable in the presence of the Beta-lactamase enzyme. As a result of the existence of beta-lactamases, many organisms resistant to penicillins and some cephalosporins may be vulnerable to Cefixime. It is absorbed 40% to 50% of the time, whether administered with or without food.

Pregnancy & Lactation

Based on available data from published studies and reports, there have been no established risks of major birth defects, miscarriage, or adverse outcomes for both the mother and the fetus associated with the use of cephalosporins, including cefixime, during pregnancy. However, it is important to note that maternal gonorrhea can have its own potential risks, such as preterm birth, low birth weight, chorioamnionitis, intrauterine growth restriction, small for gestational age, and premature rupture of membranes. There is also a risk of perinatal transmission of gonorrhea to the infant, which can lead to complications such as infant blindness, joint infections, and bloodstream infections.

Regarding lactation, there is limited information available on the presence of cefixime in human milk, its effects on breastfed infants, or its impact on milk production. However, cefixime has been found to be present in animal milk. It is important to consider the developmental and health benefits of breastfeeding alongside the mother's clinical need for therapy and any potential adverse effects on the breastfed infant, whether from the medication or the mother's underlying condition.

If you are pregnant or breastfeeding, it is crucial to discuss the use of Cef-3 Forte Powder for Suspension with your healthcare provider. They can evaluate the potential risks and benefits in your specific situation and make an informed decision regarding the appropriate course of treatment.

Precautions & Warnings

Cef-3 Forte Powder for Suspension has the potential to cause hypersensitive reactions, including severe reactions that can lead to shock and even mortality. If such a reaction occurs, it is important to discontinue the use of Cef-3 Forte Powder for Suspension.

It is not recommended to take Cef-3 Forte Powder for Suspension if you have a known allergy to Cefixime or other cephalosporin antibiotics, or if you are allergic to any of the other ingredients present in the medication. Prior consultation with a doctor is advised before taking Cef-3 Forte Powder for Suspension if you have certain conditions such as seizures, liver or renal dysfunction, heart disorders, or inflammation of the colon's inner lining (colitis).

If you are pregnant, planning to become pregnant, or breastfeeding, it is important to consult with your doctor before using Cef-3 Forte Powder for Suspension to assess the potential risks and benefits.

Cef-3 Forte Powder for Suspension may cause dizziness, so it is important to exercise caution while driving or operating machinery until you are certain of your alertness and ability to safely perform these activities.

Additionally, Cef-3 Forte Powder for Suspension may interfere with certain tests, such as urine glucose (sugar) tests, and can produce unusual results. It is advisable to inform your doctor that you are using Cef-3 Forte Powder for Suspension before undergoing any such tests to ensure an accurate interpretation of the results.

Storage Conditions

Ensure that Cef-3 Forte Powder for Suspension is kept away from children's reach. Before mixing the suspension, store it at room temperature. After mixing the suspension, store it in a refrigerator. Consume the reconstituted suspension within 7 days after opening.