Temcard 40 Tablet 1 Strip

✔️ Side Effects:

• Back pain
• Diarrhea
• Dizziness
• Nasal congestion
• Sinusitis
• Muscle pain
• Upper respiratory tract infections
• Less common or serious side effects
• Low blood pressure
• Increased blood potassium (hyperkalemia)
• Changes in kidney function
• Allergic reactions, including rare angioedema

✔️ Pregnancy & Lactation

Pregnancy: Telmisartan can cause serious fetal harm, particularly during the second and third trimesters. It should not be used during pregnancy and must be discontinued promptly under medical supervision if pregnancy is detected.

Breastfeeding: Information on telmisartan use during breastfeeding is limited. Consult a doctor to determine the most appropriate blood pressure treatment during lactation.

✔️ Temcard 40 should not be used in patients with:

• Known hypersensitivity to telmisartan or any component of the formulation.
• Severe hepatic impairment or biliary obstructive disorders.
• Pregnancy.
• Concomitant aliskiren use in patients with diabetes; use is also generally avoided in patients with significant renal impairment according to applicable prescribing guidance.

✔️ Interaction

• Digoxin: Telmisartan may increase digoxin concentrations; monitoring may be necessary.
• Lithium: May increase lithium levels and the risk of toxicity.
• Warfarin: Telmisartan may reduce warfarin plasma concentrations in some patients; monitor as clinically appropriate.
• Potassium supplements, potassium-sparing diuretics, and potassium-containing salt substitutes: May increase the risk of hyperkalemia.
• NSAIDs: May reduce the antihypertensive effect and increase the risk of kidney impairment.
• Aliskiren: Concomitant use may increase the risk of kidney dysfunction, hypotension, and hyperkalemia, particularly in patients with diabetes or renal impairment.

✔️ Dosage & Administration

Adult Dose

Hypertension:

• The usual starting dose is 40 mg once daily. Depending on blood pressure response, the dose may be adjusted within the range of 20–80 mg once daily.

Most of the blood pressure-lowering effect is apparent within two weeks, with the maximum effect generally reached after approximately four weeks.

If additional blood pressure control is required, a doctor may increase the dose or add another antihypertensive medicine, such as a diuretic.

Cardiovascular risk reduction: 

• The recommended dose is generally 80 mg once daily for eligible adults, as prescribed by the treating physician.

Elderly patients: 

• Routine initial dose adjustment is generally unnecessary, but individual clinical factors should be considered.

Hepatic impairment: 

• Lower doses and careful monitoring may be necessary. Initial treatment is not recommended in severe hepatic impairment or biliary obstructive disorders.

Pediatric Dose

• Safety and efficacy have not been established in patients younger than 18 years for the indications described above. Use should follow specialist advice and applicable prescribing guidelines.

Renal Dose

• Mild to moderate renal impairment: An initial dose adjustment is generally not required.
• Severe renal impairment: Careful dose titration and close monitoring are recommended.
• Patients receiving dialysis: Monitor blood pressure carefully because orthostatic hypotension may occur.
• Renal function and serum potassium should be assessed as clinically indicated.

✔️ Storage:

Store in a dry place away from light and heat. Keep out of the reach of children.