Angilock 50mg Tablet 10pcs

✔️ Uses of Angilock 50mg Tablet

• Hypertension
• Diabetic Nephropathy
• Hypertension with left ventricular hypertrophy

✔️ How does Angilock 50mg Tablet

Angilock 50mg Tablet inhibits the effects of Angiotensin II (a chemical generated by your body that promotes blood vessel constriction), resulting in blood vessel relaxation and low blood pressure in afflicted persons.

✔️ Side Effects of Angilock 50mg Tablet

• Stomach pain
• Difficulty or painful urination
• Back pain
• Chest tightness
• Dizziness
• Weakness in arms, hands, legs, or feet
• Sore throat
• Drowsiness
• Headache
• Cough
• Edema
• Constipation
• Diarrhea
• Low blood pressure
• Low blood sugar levels
• High potassium levels in the blood

✔️ Quick Suggestions:

• To ensure proper medication adherence, take Angilock 50mg Tablet at the same time each day. This helps you remember to take it regularly.
• During the initial days of treatment, you may experience dizziness. To minimize the risk of falling, especially after being in a seated or lying position for a prolonged period, rise slowly and allow your body to adjust.
• Your doctor may order regular blood tests to monitor the levels of urea, creatinine, and potassium in your blood. This is done to ensure the medication is working effectively and to identify any potential side effects.
• Maintaining a low-salt diet is important while taking Angilock 50mg Tablet. Processed foods tend to have higher sodium content, so try to minimize their consumption. Instead, use herbs and spices to add flavor to your meals.
• Engage in regular exercise such as cycling, walking, jogging, dancing, or swimming for at least 30 minutes every day. This helps to further manage blood pressure levels and promote overall cardiovascular health.
• Chronic stress can contribute to high blood pressure. Identify stress triggers in your life and find ways to manage or avoid them. Make time for activities you enjoy and prioritize relaxation.
• Follow a balanced diet that includes plenty of fruits, vegetables, whole grains, and low-fat dairy products. This helps to support overall cardiovascular health.
• Avoid smoking and limit alcohol intake, as they can negatively impact blood pressure control.
• Monitor your blood pressure regularly and consult a doctor if you notice any significant fluctuations or concerns.
• Remember, a low-salt diet and regular exercise are essential components of managing high blood pressure alongside Angilock 50mg Tablet for optimal results.
• Consult your doctor before taking any anti-inflammatory medications like ibuprofen while on Angilock 50mg Tablet.
• If you are pregnant or breastfeeding, do not take Angilock 50mg Tablet without consulting your doctor, as it may pose risks to the baby.
• Do not discontinue the medication abruptly without discussing it with your doctor. They will provide guidance on the appropriate course of action.

✔️ Indication

Angilock 50mg Tablet is a blood pressure-lowering medicine. It is used alone or in combination with other medicines for the treatment of hypertension (high blood pressure) and to help protect the kidneys from damage due to diabetes. It is also used to reduce the risk of stroke (a condition that occurs due to reduced blood supply to the brain). Angilock 50mg Tablet works by relaxing your blood vessels and lowering your blood pressure. 

✔️ Pharmacology

Angilock 50 is a medication belonging to the class of non-peptide angiotensin II receptor blockers. It is the first orally active drug in this class. The drug works by binding to angiotensin II type 1 (AT1) receptors, which are present in various tissues including vascular smooth muscle, adrenal glands, kidneys, and heart.

By binding to these receptors, Angilock 50mg Tablet reduces several important biological effects that are mediated by angiotensin II. This includes the inhibition of vasoconstriction, which helps to relax and widen blood vessels, leading to a decrease in blood pressure. Additionally, Angilock 50 inhibits the release of aldosterone, a hormone that plays a role in the regulation of blood pressure by promoting sodium and water retention.

Overall, Angilock 50mg Tablet helps to lower high blood pressure by blocking the effects of angiotensin II, resulting in vasodilation and reduced fluid retention. By inhibiting vasoconstriction and aldosterone release, it helps to improve cardiovascular function and reduce the strain on the heart.

✔️ Dosage & Administration of Angilock 50mg Tablet

• For adults, the usual dose of Angilock 50mg Tablet for hypertension is 50 mg taken once daily. If needed, the dose can be increased to 100 mg per day, either as a single dose or divided into two doses. For patients with intravascular volume depletion, the initial dose is 25 mg once daily.
• In cases of diabetic nephropathy in Type 2 diabetes mellitus, the initial dose is 50 mg once daily, which may be increased to 100 mg once daily based on blood pressure response.
• For conditions such as heart failure, hypertension with left ventricular hypertrophy, and stroke risk reduction in hypertensive or LVH patients, the initial dose is 50 mg once daily.
• In some cases, hydrochlorothiazide may be added to the treatment. The dose of Losartan can be increased to 100 mg once daily, and hydrochlorothiazide can be increased to 25 mg once daily based on blood pressure response.
• For children with hypertension, the dose is based on body weight. For children weighing between 20-50 kg, the initial dose is 0.7 mg/kg, not exceeding a maximum dose of 50 mg per day. For children weighing over 50 kg, the initial dose is 1.4 mg/kg, not exceeding a maximum dose of 100 mg per day.
• In patients with renal impairment and creatinine clearance (CrCl) of less than 20 ml/min, the initial dose is 25 mg once daily.

It's important to note that the dosage may vary depending on individual factors and should be determined by a healthcare professional. Regular monitoring and follow-up with a doctor are crucial to ensure the effectiveness and safety of the medication.

✔️ Interaction

• Angilock 50mg Tablet may interact with various medications and substances. Here are some of the interactions to be aware of:
• Painkillers (ibuprofen, aspirin): These medications may reduce the effectiveness of Angilock 50mg Tablet in lowering blood pressure.
• High blood pressure lowering medicines (lisinopril, enalapril, ramipril, etc.): Taking Angilock 50mg Tablet along with other medications that lower blood pressure may lead to a further decrease in blood pressure. Close monitoring is necessary.
• Water pills (amiloride, spironolactone, triamterene): Concurrent use of Angilock 50mg Tablet with water pills may increase the risk of high potassium levels in the blood (hyperkalemia). Regular monitoring of potassium levels is important.
• Blood thinners (heparin): There is a potential risk of increased bleeding if Angilock 50mg Tablet is used together with blood thinners like heparin. Careful monitoring is required.
• Muscle relaxant (tizanidine): Combining Angilock 50mg Tablet with tizanidine may lead to low blood pressure and dizziness. Caution is advised.
• Antibiotics (trimethoprim): Concurrent use of trimethoprim and Angilock 50mg Tablet may increase the risk of high potassium levels in the blood. Regular monitoring is recommended.
• Additionally, Angilock 50mg Tablet may interact with potassium salt substitutes, potassium supplements, and grapefruit or its juice, which may increase the levels of potassium in the blood.
• It's important to inform your doctor about all the medications, including over-the-counter drugs and supplements, that you are taking. They can provide guidance on potential interactions and adjust your treatment accordingly.
• People with angioedema, low blood pressure (hypotension), diabetes, kidney problems, liver problems, and heart problems should consult their doctor before taking Angilock 50mg Tablet , as special precautions or dosage adjustments may be necessary.
• Regular monitoring and follow-up with a healthcare professional are crucial to ensure the safe and effective use of the Angilock 50mg Tablet.

✔️ Contraindications

Losartan potassium should not be used in patients who have a known hypersensitivity or allergy to the active ingredient or any other component of the medication. It is also contraindicated in patients with severe hepatic impairment and during pregnancy. Additionally, concomitant use of losartan potassium with aliskiren is not recommended in patients with diabetes and renal impairment, specifically when the glomerular filtration rate (GFR) is less than 60 mL/min.

✔️ Pregnancy & Lactation

Angilock 50 is classified as Pregnancy Category D, meaning that it may pose risks to the fetus if taken during the second or third trimester of pregnancy. It is important to weigh the potential benefits of the medication against the potential risks to the unborn baby. It is also unclear whether losartan potassium is excreted into human milk. Since many drugs are excreted into breast milk and may have adverse effects on infants, a decision should be made considering whether to discontinue breastfeeding or stop taking the medication, taking into account the importance of the drug for the mother's health. It is advised to consult with a healthcare professional for personalized advice regarding the use of Angilock 50 during pregnancy or while breastfeeding.

✔️ Precautions & Warnings

Before taking Angilock 50mg Tablet, it is important to inform your doctor if you have diabetes, kidney, or liver problems. Pregnant women, especially during the second and third trimesters, are advised not to take Angilock 50mg Tablet as it can potentially cause harm to the unborn baby (fetus). Breastfeeding women should also consult their doctor before taking the medication. Alcohol consumption should be avoided as it can increase the risk of low blood pressure. Additionally, it is important to avoid potassium supplements while taking Angilock 50mg Tablet to prevent high potassium levels in the blood. Regular blood tests and blood pressure monitoring are recommended while using the medication. It is crucial to follow your doctor's advice and guidance throughout the treatment.

✔️ Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.