Sucralfate exhibits a local effect in the gastrointestinal tract as it is minimally absorbed systemically. Once administered, it binds to ulcerated areas, forming a viscous, protective barrier. This protective layer shields the ulcer site from pepsin, gastric acid, and bile, facilitating healing. The small amount absorbed is primarily excreted through the urine.
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Proper Packaging
Ulfix 1000 is prescribed for individuals aged 14 years and older in the management of:
Gastrointestinal protectants – Chelating complex
For Duodenal & Gastric Ulcers, Chronic Gastritis:
Adults: 2 g twice daily (morning and bedtime), or 1 g four times daily (one hour before meals and at bedtime).
Maximum daily dose: 8 g.
Treatment may continue up to 12 weeks in resistant cases.
For Stress Ulcer Prophylaxis:
Adults: 1 g, 4 to 6 times daily, orally or via nasogastric tube.
Follow each nasogastric dose with 10 ml of water to prevent clogging.
Duration: As long as stress ulcer risk factors persist (typically not exceeding 14 days).
Take on an empty stomach. Avoid antacids within 30 minutes of taking Ulfix.
Children (<14 years): Safety and efficacy not established.
Elderly: Use the lowest effective dose; no specific adjustment required.
Renal Impairment: Use cautiously due to the risk of aluminum accumulation.
Common Adverse Reactions:
Others (Rare or Undefined Frequency):
Ulfix may impair the absorption of several medications, including:
Overdose is generally well tolerated. Minor symptoms such as nausea, abdominal discomfort, or vomiting may occur. Animal studies show low toxicity even at high doses.
Known hypersensitivity to Sucralfate or any component of the formulation.
Store below 25°C in a cool, dry place away from direct light. Keep out of reach of children.
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