Generic Name: Magaldrate + Simethicone
Manufacturer/Distributor: Square Pharmaceuticals Ltd.
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Indications
Hyperacidity, gastric and duodenal ulcer, gastritis, heartburn, dyspepsia, gastroesophageal reflux. It is also indicated for the relief of flatulence, abdominal distention, and windy colic.
Pharmacology
Magaldrate neutralizes gastric acid, thereby increasing the pH of the stomach and duodenal bulb. It also increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying. Simethicone lowers the surface tension of gas bubbles.
Dosage & Administration
MagantaTM Plus Tablet: 1-4 chewable tablets, 20 to 60 minutes after meals and at bedtime, or as directed by the physician. MagantaTM Plus Suspension: 2-4 teaspoonfuls (10-20 ml) of suspension, 20 to 60 minutes after meals and at bedtime, or as directed by the physician.
Interaction
It ought to not be utilized in patients taking any frame of Tetracycline. The medication may cause decreased bio-availability or slower retention of a number of drugs counting propranolol, isoniazid, prednisolone, and naproxen.
Contraindications
Intestinal obstruction, renal function impairment, appendicitis, chronic diarrhea, sensitivity to aluminum, magnesium, and simethicone.
Side Effects
Constipation, diarrhea, intestinal pain.
Pregnancy & Lactation
Pregnancy category C so should be used in pregnancy only when necessary. Chronic high doses should be avoided.
Children: Not recommended under 6 years of age unless properly diagnosed.
Precautions & Warnings
Should be cautious, if allergic to any ingredient to Magaldrate and Simethicone suspension, with a history of kidney problems, or taking citrate salts (found in some calcium supplements, antacids, and laxatives). Do not take tetracycline antibiotics. Antacids can interfere with the absorption of iron preparation.
Storage Conditions
Store in a cool and dry place. Protect from light. Keep out of the reach of children.
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