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Esomups 20 | 6pcs Tablet
Esomups 20 mg: Each MUPS tablet contains 133.33 mg enteric-coated pellets equivalent to 20 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP)
Esomups 40 mg: Each MUPS tablet contains 266.67 mg enteric-coated pellets equivalent to 40 mg Esomeprazole
- Do not eat close to bedtime to reduce reflux risk
- Report persistent diarrhea or abdominal pain
- Maintain adequate calcium & magnesium intake
- Watch for signs of kidney problems with long-term use
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✅ Description:
Esomeprazole is a proton pump inhibitor (PPI) that blocks the H+/K+-ATPase enzyme system in gastric parietal cells, thereby suppressing gastric acid secretion. It is effective in healing acid-related mucosal damage and preventing recurrence.
Esomups is indicated for:
- Gastroesophageal Reflux Disease (GERD)
- Prevention of gastric ulcers associated with NSAID use
- Eradication of Helicobacter pylori (as part of triple therapy)
- Zollinger-Ellison syndrome and other pathological hypersecretory conditions
Use only as advised by a registered physician.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ MUPS Technology Advantage
MUPS (Multiple-Unit Pellet System) offers:
- Enhanced bioavailability
- Even drug release with minimized risk of dose dumping
- Better gastric tolerance and esophageal clearance
- Rapid onset (early Tmax and Cmax) and sustained acid suppression
- More consistent absorption and plasma concentration stability
✔️ Side Effects
- Headache
- Diarrhea
- Nausea
- Abdominal pain
- Flatulence
- Constipation
- Dry mouth
✔️ Dosage & Administration
GERD, Erosive Esophagitis (≥12 yrs): 40 mg once daily for 4 weeks
Maintenance (≥12 yrs): 20 mg once daily
NSAID-related ulcer prevention (adults): 20 mg daily for 4–8 weeks
H. pylori eradication (with Amoxicillin & Clarithromycin): 20 mg twice daily for 7 days
Zollinger-Ellison syndrome: 40–80 mg twice daily
Children 1–11 years: Weight-based dosing (10–20 mg once daily)
Not recommended under 1 year of age.
✔️ Administration Guidance
- Swallow whole with water. Do not crush or chew.
- May be dispersed in ½ glass of non-carbonated water and taken immediately (within 30 minutes).
- Rinse and drink the remaining suspension to ensure full dose.
- Do not use mineral water or any other liquid.
✔️ Interaction
- Metabolized primarily by CYP2C19 and CYP3A4
- May raise diazepam levels (CYP2C19 substrate)
- Reduced absorption of drugs like ketoconazole, iron salts, and digoxin due to increased gastric pH
- No significant interaction with phenytoin, warfarin, oral contraceptives, quinidine, clarithromycin, or amoxicillin
✔️ Contraindications
- Known hypersensitivity to esomeprazole or other components of the formulation
Side effects are similar in short- and long-term usage.
✔️ Pregnancy & Lactation
Use with caution.
Safety in pregnancy and lactation not fully established.
Discuss risks and benefits with a physician.
✔️ Precautions & Warnings
Caution in severe liver or kidney impairment
Long-term use may slightly increase the risk of fractures (hip, spine, wrist)
May lead to magnesium deficiency; supplementation might be needed
✔️ Storage Condition
Store below 25°C, in a cool, dry place, away from light.
Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
