Voriconazole works by inhibiting the fungal enzyme 14-alpha-demethylase, which is necessary for ergosterol production. Ergosterol is an essential component of the fungal cell membrane. By disrupting its production, voriconazole inhibits fungal growth.
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Caspa contains voriconazole, a triazole antifungal medicine used to treat serious fungal infections in adults and children aged 12 years and older, including:
Caspa should not be used in patients with known hypersensitivity to voriconazole or any of its ingredients. It is also contraindicated with certain medicines because of potentially serious interactions, including some medicines that affect heart rhythm, sirolimus, rifampin, carbamazepine, long-acting barbiturates, and St. John's wort.
The dose and duration depend on the type and severity of infection, body weight, liver function, and other medicines being taken. Caspa should be used only under the supervision of a registered physician.
Oral tablets and suspension:
There are insufficient controlled studies in pregnant women. Voriconazole should be used during pregnancy only when the potential benefit justifies the potential risk to the fetus. Consult a physician before using it while breastfeeding.
Safety and effectiveness are not established for children younger than 12 years in the product information provided. Pediatric use requires specialist guidance.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.