Human Chorionic Gonadotrophin (hCG) is a prescription injectable hormone used in selected fertility and reproductive health treatments for both women and men. With its LH-like activity, hCG helps support key reproductive processes—such as triggering ovulation in women and stimulating testosterone production in men. Because fertility treatment often depends on precise hormone timing, hCG should be used strictly according to a specialist's instructions.
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Human Chorionic Gonadotrophin may be prescribed for several fertility and hormone-related conditions, including:
Human Chorionic Gonadotropin works by mimicking the action of luteinizing hormone (LH), helping activate important reproductive pathways.
Most side effects are mild, but some require prompt medical attention.
Women undergoing fertility treatment should be particularly alert for symptoms of ovarian hyperstimulation syndrome (OHSS), which can occasionally become serious.
Contact your doctor urgently if you develop:
In women, hCG can act like the body's natural LH surge, helping complete follicular maturation and trigger ovulation. This makes it an important component of certain medically supervised fertility protocols.
In men with hypogonadotropic hypogonadism, hCG stimulates the Leydig cells in the testes, encouraging natural testosterone production and supporting reproductive function.
When used alongside appropriate FSH treatment, hCG may help create the hormonal environment required for sperm production in men with certain forms of infertility.
A healthy lifestyle can complement medically supervised fertility treatment:
Timing matters in fertility treatment. Keep a clear record of your injection schedule and follow your doctor's instructions precisely. Regular ultrasound and laboratory monitoring may be required to assess follicular development and treatment response.
Women receiving ovarian stimulation should be especially aware of OHSS. Seek medical attention promptly if you experience severe abdominal or pelvic pain, marked bloating, sudden weight gain, breathing difficulty, persistent vomiting, swelling, or reduced urine output.
Tell your doctor about every medicine, vitamin, supplement, or fertility treatment you are taking. When hCG is combined with other gonadotropins or ovarian-stimulating medicines, careful monitoring may be necessary because excessive ovarian stimulation can occur.
hCG should not be used as a fertility treatment during pregnancy. If pregnancy occurs during treatment, contact your healthcare provider.
Use during breastfeeding should only be considered when specifically advised by a healthcare professional.
Kidney disease
Men with androgen-dependent cancers, such as prostate cancer, should not use hCG unless specifically evaluated and directed by a specialist.
In boys, hCG can stimulate testosterone production and may cause premature sexual development. Treatment should therefore be carefully monitored.
Store Human Chorionic Gonadotrophin according to the specific product's label instructions. Some preparations require refrigeration at 2–8°C, while certain products may permit limited storage below 25°C. Do not freeze, and protect the medicine from light and moisture where applicable.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.