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Generic Name: Ambroxol 15 mg/5 ml Syrup
Manufacturer/Distributor: Globe Pharmaceuticals Ltd.
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✅ Description:
Indications
Femex is used to treat a variety of respiratory tract conditions brought on by an abundance of mucus. It functions by making mucus in the lungs, windpipe, and nose thinner and looser so that it is easier to cough out. It is best to take Femex with food. It is advised to take it at the same time each day for best benefits. Depending on what you are using it for, you should adjust the dosage and frequency. How much improvement in your symptoms is required will be decided by your doctor. It is suggested against using it for longer than 14 days without consulting a doctor.
Pharmacology
Femex 100 ml is the active metabolite of bromhexine, and it has been shown that it has a higher bronchosecretolytic action than bromhexine. It improves sputum rheology by hydrating the mucus in the lumen of the respiratory tract, allowing for easier mucus expectoration and decreasing dyspnea. It increases the synthesis of surfactant phospholipids by alveolar cells, which contributes to the reduction of surface tension in the alveoli.It also helps to decrease bronchial hyperactivity. Because of its inhibitory impact on the synthesis of cellular cytokines and arachidonic acid metabolites, ambroxol possesses anti-inflammatory effects. It has historically been shown to enhance airway patency in COPD patients.
Dosage & Administration
Average daily dose (preferably after meal):
Pediatric Drops:
0-6 months: 0.5 ml 2 times a day
6-12 months: 1 ml 2 times a day
1-2 years: 1.25 ml 2 times a day
Syrup:
2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
10 years and adults: 10 ml (2 teaspoonful) 3 times a day.
Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily.
Interaction
Femex 100 ml should not be used concurrently with antitussives (e.g., codeine) because phlegm liquefied by Ambroxol may not be expectorated.
Contraindications
Ambroxol or Bromhexine hypersensitivity is contraindicated.
Side Effects
Gastrointestinal side effects such as epigastric discomfort and a sense of stomach overfilling may occur on occasion. Allergic reactions such as eruption, urticaria, or angioneurotic edema have been recorded on rare occasions.
Pregnancy & Lactation
Teratogenic and fetal toxicity investigations have revealed that Femex 100 ml has no negative effects. However, it is not recommended to use it during pregnancy, especially during the first trimester. Lactation safety has yet to be established.
Precautions & Warnings
Femex 100 ml should be used with caution in individuals with stomach and duodenal ulcers, as well as convulsive disorders. Patients with hepatic and renal impairment should avoid it.
Storage Conditions
Avoid direct sunlight exposure. Store in a cool, dry area with a temperature no higher than 30°C. Keep out of children's reach.
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