Uroflo Plus 0.4mg+0.5mg Capsule

✔️ Benefits:

Relief from Urinary Symptoms

• Helps reduce difficulty while passing urine
• Improves bladder emptying
• Decreases frequent urination, especially during the night
• Supports smoother and more comfortable urine flow

Long-Term Prostate Management

• Helps reduce prostate size over time
• May lower the likelihood of surgery related to acute urinary retention when used regularly under medical supervision

✔️ How to Take Uroflo Plus 0.4 mg+0.5 mg Capsule

• Take the capsule at the same time every day.
• It is generally recommended to take it about 30 minutes after a meal, preferably breakfast.
• Swallow the capsule whole with water.
• Do not chew, crush, or open the capsule.
• Continue treatment regularly, even if symptoms improve, as full benefits may take several weeks to become noticeable.

✔️ Missed Dose

If you forget a dose, take it as soon as you remember. If it is nearly time for the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate for a missed one.

✔️ How Uroflo Plus 0.4mg+0.5mg Capsule Works

Dual-Action Formula

Uroflo Plus 0.4mg+0.5mg Capsule combines two medicines that target different causes of BPH symptoms:

Tamsulosin

Tamsulosin is an alpha-1 receptor blocker that relaxes the smooth muscles of the prostate and bladder neck. This relaxation helps urine pass more easily and relieves symptoms such as urinary urgency, hesitancy, and poor urine flow.

Dutasteride

Dutasteride is a dual 5-alpha-reductase inhibitor that reduces the conversion of testosterone into dihydrotestosterone (DHT), a hormone responsible for prostate growth. Lower DHT levels gradually reduce prostate size and help address the underlying cause of BPH.

Targeted Action

Tamsulosin primarily acts on receptors located in the prostate and urinary tract, helping minimize effects on blood vessels and reducing the likelihood of significant blood pressure changes. Dutasteride inhibits both Type I and Type II 5-alpha-reductase enzymes, providing consistent suppression of DHT and effective long-term reduction in prostate size.

✔️ Side Effects

Common Side Effects

• Dizziness
• Lightheadedness
• Drowsiness
• Reduced sexual desire
• Changes in ejaculation or semen volume
• Breast tenderness or enlargement

Serious Side Effects

Seek immediate medical attention if you experience:

• Rash, itching, or hives
• Swelling of the face, lips, eyelids, arms, or legs
• Difficulty breathing
• Severe skin reactions with blistering or peeling (including Stevens-Johnson Syndrome)

✔️ Dosage and Administration

Recommended Dose

The usual adult dosage is:

• One capsule once daily

Each capsule contains:

• Dutasteride 0.5 mg
• Tamsulosin 0.4 mg

Dosage adjustments may be required based on individual medical conditions and physician recommendations.

✔️ Drug Interactions

Tell your doctor if you are taking:

Alpha-Blockers

• Prazosin
• Doxazosin
• Terazosin

Erectile Dysfunction Medicines

• Sildenafil
• Tadalafil
• Vardenafil

Antifungal Medicines

• Ketoconazole
• Itraconazole
• Terbinafine

Calcium Channel Blockers

• Verapamil
• Diltiazem

Antidepressants

• Paroxetine
• Nefazodone

Blood Thinners and Anti-Inflammatory Medicines

• Warfarin
• Diclofenac

Other Medicines

• Cimetidine
• Erythromycin
• Ritonavir
• Indinavir

These medicines may alter the effectiveness of Uroflo Plus 0.4mg+0.5mg Capsule or increase the risk of side effects.

Food and Allergy Considerations

Patients with soy or peanut allergies should avoid this medicine. Always discuss dietary restrictions and allergy concerns with your healthcare provider before starting treatment.

✔️ Taking more than the prescribed dose may result in:

• Severe dizziness
• Low blood pressure
• Nausea
• Vomiting

Seek immediate medical attention if an overdose is suspected.

✔️ Do not take Uroflo Plus 0.4mg+0.5mg Capsule if you:

• Are allergic to Tamsulosin, Dutasteride, soy, peanuts, or any ingredient in the formulation
• Have severe liver disease
• Have a history of orthostatic hypotension (sudden blood pressure drop when standing)
• Are a woman, child, or adolescent under 18 years of age

✔️ For better management of BPH symptoms:

• Stay adequately hydrated during the day
• Reduce caffeine and alcohol intake
• Engage in regular physical activity
• Maintain a balanced diet rich in fruits, vegetables, and healthy fats
• Attend regular medical checkups and PSA screenings

✔️ Adherence Tips

• Take the capsule at the same time daily.
• Use reminders, alarms, or pill organizers to avoid missed doses.
• Continue treatment as prescribed, even if symptoms improve gradually.
• Discuss any side effects with your healthcare provider before discontinuing therapy.

✔️ Long-Term Monitoring

Since BPH is a chronic condition, long-term treatment may be necessary. Regular follow-up appointments help evaluate:

• Symptom improvement
• PSA levels
• Treatment effectiveness
• Possible side effects
• Liver and overall health status

✔️ Before Using Uroflo Plus 0.4mg+0.5mg Capsule Inform your doctor if you:

• Have liver or kidney disease
• Have low blood pressure or heart-related conditions
• Are scheduled for cataract or glaucoma surgery
• Are taking other prescription medicines, supplements, or herbal products
• Need regular PSA (Prostate-Specific Antigen) testing

Pregnancy and Handling Precautions

Uroflo Plus 0.4mg+0.5mg Capsule is intended exclusively for adult men.

• Women who are pregnant, planning pregnancy, or breastfeeding should not use or handle damaged capsules.
• Dutasteride can be absorbed through the skin and may affect the development of a male fetus.
• Men whose partners are pregnant or may become pregnant should consider using condoms during treatment.

Alcohol

Avoid or limit alcohol consumption while taking Uroflo Plus 0.4mg+0.5mg Capsule, as alcohol may increase dizziness and drowsiness.

Driving and Machinery

Use caution when driving or operating machinery, particularly when starting treatment, as dizziness or drowsiness may occur.

Kidney Impairment

Use cautiously in patients with severe kidney disease and follow medical advice closely.

Elderly Patients

Patients over 65 years of age may be more sensitive to certain side effects and should be monitored regularly.

✔️ Storage:

• Store in a cool, dry place.
• Protect from heat, moisture, and direct sunlight.
• Keep out of reach of children.