Flexibac 5mg Tablet

Uses of Flexibac 5mg Tablet

• Treats Muscle Spasms (painful muscle contractions)

How does Flexibac 5mg Tablet work?

Flexibac is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the spinal cord that induces muscle relaxation. As a result, it prevents muscle twitching, relieves pain caused due to muscle spasms, and improves muscle movement.

Side Effects of Flexibac 5mg Tablet

• Nausea
• Vomiting
• Tiredness
• Sleepiness
• Weak limbs
• Muscle pain
• Constipation,
• Dry mouth
• Diarrhea,
• Lack of sleep, nightmares
• Confusion, hallucination
• Breathing difficulties
• Vision problems
• Urge to pass urine
• Feeling unsteady or shaky
• Feeling faint due to low blood pressure
• Skin rash, sweating
• Increased liver enzymes

Quick Suggestions:

• Relief from Muscle Rigidity and Spasticity: Flexibac 5mg Tablet provides relief from rigidity, tension, and stiffness in muscles, particularly spasticity caused by conditions affecting the nervous system.
• Taking with Food or Milk: It is recommended to take Flexibac 5mg Tablet with or after food or with a glass of milk. This can help minimize potential stomach discomfort.
• Regular Exercise and Muscle Stretching: Regular exercise, including mild activities like jogging and walking, can help stretch the muscles and reduce the likelihood of spasms, tears, and sprains. Consult with a healthcare professional or physical therapist for appropriate exercise recommendations.
• Massage Therapy: Massages can be beneficial in relieving muscle tension and spasticity. Consider consulting a qualified massage therapist for appropriate techniques and guidance.
• Temperature Sensitivity: Avoid exposing yourself to extremely cold or hot temperatures, as it may exacerbate muscle symptoms.
• Loose Clothing: Opt for loose-fitting garments instead of tight-fitting clothes to ensure comfort and minimize unnecessary pressure on muscles.
• Adequate Rest and Sleep: Rest is essential for muscle recovery. Ensure you get plenty of sleep and maintain a regular sleep schedule.
• Position Changes: To prevent pressure sores, change your position at least every two hours, especially if you have limited mobility.
• Hot or Cold Therapy: Hot or cold packs can provide relief from muscle spasms. Apply an ice pack or hot pack to the affected muscle for 15-20 minutes as directed by your healthcare professional.
• Hydration: Stay hydrated by drinking plenty of water to support overall muscle health and function.
• Regular Liver Function Tests: Your doctor may advise regular blood tests to monitor liver function while taking Flexibac 5mg Tablet. Follow their recommendations and attend the scheduled tests.
• Surgery and Anesthesia: Inform your doctor that you are taking Flexibac 5mg Tablet if you are scheduled to undergo surgery requiring general anesthesia.
• Mental Health Considerations: Contact your doctor immediately if you experience mood swings, depression, or have any suicidal thoughts while taking Flexibac 5mg Tablet.
• Drowsiness and Concentration: Flexibac 5mg Tablet may cause dizziness or sleepiness. Avoid driving or engaging in activities that require concentration until you know how the medication affects you.
• Alcohol Consumption: It is advised to avoid consuming alcohol while taking Flexibac 5mg Tablet, as it may enhance drowsiness.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to conceive, or breastfeeding. They will evaluate the potential risks and benefits and provide appropriate guidance.
• Gradual Discontinuation: If you have been taking Flexibac 5mg Tablet for a long time, do not stop taking it suddenly without consulting your doctor. They will provide guidance on gradually reducing the dosage if needed.

Indication

Flexibac 5mg Tablet is used in treating the symptoms of muscle spasticity (stiffness and tightness) that may be due to multiple sclerosis (a disease affecting the brain or spinal cord), any injury of the brain or spine, any diseases of the spinal cord, etc.

Pharmacology

Baclofen is a medication that works by activating GABAB receptors in the spinal cord. This activation leads to the inhibition of the release of certain neurotransmitters, such as glutamate and aspartate. By reducing the release of these excitatory neurotransmitters, baclofen helps to modulate the transmission of nerve signals in the spinal cord.

Baclofen's primary mechanism of action involves reducing both monosynaptic and polysynaptic reflexes. Monosynaptic reflexes are rapid and automatic responses of the nervous system, while polysynaptic reflexes involve multiple synaptic connections. By inhibiting these reflexes, baclofen can help to reduce muscle spasticity, rigidity, and tension.

Furthermore, baclofen can cause central nervous system depression by acting on intraspinal sites. This depression can lead to sedation and muscle relaxation, contributing to the medication's therapeutic effects.

Additionally, baclofen has been found to possess pain-relieving properties. It may help to alleviate certain types of pain, particularly those associated with muscle spasticity or conditions affecting the nervous system.

Dosage & Administration of Flexibac 5mg Tablet

• The recommended adult oral dose for spasticity is to start with 5 mg three times daily for three days, then increase to 10mg three times daily for another three days. The dosage may then be increased gradually at similar intervals until the desired effect is achieved or up to a maximum of 80 mg per day. The elderly should initiate with lower doses.
• For children with spasticity, the oral dose is 0.75-2 mg/kg daily. The initial dose may be 2.5 mg four times daily, increased gradually every three days until the desired effect is achieved. The maintenance dose is 30-60 mg daily for 6-10-year-olds, 20-30 mg daily for 2-6-year-olds, and 10-20 mg daily for children aged 12 months to 2 years. The maximum dose for children over 10 years old is 2.5 mg/kg daily.
• Dose reduction may be necessary for individuals with renal impairment.

Interaction

• Drug-Drug Interactions: Flexibac 5mg Tablet may interact with various medications, including painkillers (such as hydrocodone, methadone, acetaminophen, ibuprofen, morphine, fentanyl, and tramadol), opiate antagonists (naloxone), muscle relaxants (tizanidine), mood disorder medications (lithium, amitriptyline), calcium channel blockers (diltiazem), medications used for Parkinson's disease (levodopa, carbidopa), anti-histamines (promethazine), sedative medications (temazepam), and anti-convulsants (carbamazepine).
• Drug-Food Interactions: It is advised to avoid consuming alcohol while taking Flexibac 5mg Tablet, as it can lead to increased sleepiness, drowsiness, and difficulty concentrating.
• Drug-Disease Interactions: If you have kidney dysfunction, seizures (fits), psychosis (a severe mental disorder with impaired thoughts and emotions), or autonomic dysreflexia (spinal cord injury), it is important to inform your doctor before using Flexibac 5mg Tablet.

Contraindications

• If you are allergic to Baclofen or any other ingredients of the Flexibac 5mg Tablet.
• If you had a stomach ulcer.

Pregnancy & Lactation

Baclofen is not safe to use during pregnancy, according to pregnancy category B3. Baclofen passes through the placental barrier. Baclofen should only be given to pregnant women if the physician believes that the potential benefits outweigh the potential risks. Baclofen is excreted in breast milk, but the evidence so far suggests that the amounts are so small that no adverse effects on the infant are expected.

Precautions & Warnings

• Allergies and Stomach Ulcer: Do not take Flexibac 5mg Tablet if you are allergic to any of its components or if you have a history of stomach ulcers.
• Pre-existing Medical Conditions: Before taking Flexibac 5mg Tablet, it is important to talk to your doctor if you have kidney or liver problems, mental disorders, breathing difficulty or lung disease, diabetes, difficulty in urination, high blood pressure, Parkinson's disease, or if you have a history of stroke.
• Pregnancy and Breastfeeding: Consult your doctor before taking Flexibac 5mg Tablet if you are pregnant or breastfeeding. Your doctor will weigh the potential risks and benefits before recommending its use.
• Age and Weight Restrictions: Flexibac 5mg Tablet is not recommended for children below four years of age and those who weigh below 33 kg.

Storage Conditions

Store below 30°C, away from light, in a cool, dry place. Keep out of children's reach.