Baclofen is a muscle relaxant. It acts by increasing the effects of certain chemical messengers (such as GABA) in the spinal cord that induce muscle relaxation.
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Beklo is indicated for:
Baclofen reduces both monosynaptic and polysynaptic reflexes at the spinal level by activating GABAB receptors, which decreases the release of glutamate and aspartate. It may also act within the spinal cord to cause CNS depression and provide an antinociceptive effect.
Beklo is suitable for children and adolescents under 18 if prescribed. Not for use in children weighing below 33 kg. Consult a doctor for guidance.
Use with caution in elderly patients.
Severe overdose requires gastric lavage. Symptoms include drowsiness, respiratory difficulties, fainting, muscle weakness, confusion, hallucinations, seizures, low blood pressure, slow heartbeat, nausea, vomiting, diarrhea, excessive salivation, and reflex problems.
Baclofen is contraindicated in patients with hypersensitivity to any component of the product.
Common side effects include transient drowsiness, daytime sedation, dizziness, weakness, and fatigue. Less common effects involve:
Pregnancy category B3. Baclofen's safety in pregnancy is unestablished and it crosses the placental barrier. Use only if benefits outweigh risks. Baclofen is excreted in breast milk, but quantities are minimal and likely safe for infants.
Store below 30°C, away from light and moisture. Keep out of children's reach.
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