Generic Name: Montelukast 4mg
Manufacturer/Distributor: Unimed & Unihealth Manufacturers Ltd.
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Provair 4 is indication:
A prescription drug called Provair 4 is used to prevent asthma attacks and to relieve allergy symptoms including runny nose and sneezing. Breathing becomes easier as a result of decreased airway irritation. Provair 4 can be taken with or without food, however, the best results come from taking it simultaneously. If you have asthma brought on by exercise, it is suggested that you take it two hours before activity. It should be regarded as medical advice.
Pharmacology
The cysteinyl leukotriene receptor is inhibited by the selective and orally active leukotriene receptor antagonist known as Montelukast (CysLT1). The arachidonic acid metabolism results in the production of cysteinyl leukotrienes (LTC4, LTD4, and LTE4) from a variety of cells, including mast cells and eosinophils. The pathophysiology of asthma and allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, have been linked to cysteinyl leukotrienes and leukotriene receptor occupation. These factors all contribute to the signs and symptoms of asthma.
Dosage
Adults & adolescents (15 years & older)-
Asthma & Allergic Rhinitis: 10 mg/day
Exercise-Induced Bronchoconstriction: 10 mg/day
Pediatric patients (6 to 14 years)-
Asthma & Allergic Rhinitis: 5 mg/day
Exercise-Induced Bronchoconstriction: 5 mg/day
Pediatric patients (6 months to 5 years)-
Asthma & Allergic Rhinitis: 4 mg/day
Exercise-Induced Bronchoconstriction: Not recommended
Patients who suffer from allergic rhinitis, as well as asthma, should only take one tablet per day in the evening. A single dose should be administered at least two hours prior to activity to avoid acute exercise-induced bronchoconstriction.
Administration
Route of administration: Oral. Provair 4 may be taken with or without food or as directed by the physician.
Interaction
Theophylline, prednisone, prednisolone, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, sedative-hypnotics, non-steroidal anti-inflammatory drugs, benzodiazepines, decongestants, oral contraceptives, and CYP enzyme inducers can all be taken with Montelukast without changing the dose.
food and others: Food and other factors did not significantly affect the bioavailability or other conditions.
Contraindications
Patients who are hypersensitive to any ingredient in Provair 4 should avoid using it.
Side Effects
Common symptoms include diarrhea, fever, gastrointestinal distress, headache, nausea, and vomiting, as well as skin reactions and upper respiratory tract infections.
Among the less common symptoms are akathisia, anxiety, arthralgia, asthenia, aberrant behavior, depression, dizziness, drowsiness, dry mouth, heed mage, irritability, malaise, muscle complaints, edema, seizure, and sleep difficulties.
Uncommon symptoms include angioedema, disorientation, erythema nodosum, hallucinations, hepatic issues, memory loss, palpitations, pulmonary eosinophilia, suicidal thoughts, and tremor.
Pregnancy & Lactation
There are no adequate and well-controlled studies on pregnant women. Montelukast should be used during pregnancy only if clearly needed. Provair 10 is excreted in breast milk. So caution should be exercised when Montelukast is given to a nursing mother.
Precautions & Warnings
Provair 4 is not recommended for use in treating status asthmatic or acute asthma attacks with bronchospasm. Agitation, anger, anxiety, sadness, disorientation, attention disturbance, odd dreams, hallucinations, insomnia, irritability, memory impairment, restlessness, somnambulism, suicidal thoughts and conduct (including suicide), and tremor are only a few examples of neuropsychiatric events.
Storage Conditions
Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.