Odmon 10mg Tablet

Uses of Odmon 10mg Tablet

Treat-

• Asthma
• Allergic rhinitis
• Exercise-Induced bronchospasm

Side Effects of Odmon 10mg Tablet

• Headache
• Stomach pain
• Body aches or Pain
• Pus in urine
• Agitation and anxiety
• Skin rash
• Heartburn
• Blurred vision
• Infection of the airways
• Swelling of face, lips, eyelids, tongue, hands and feet
• Nausea or Vomiting
• Diarrhea
• Fever

How does work?

MONTAIR 10MG TABLET effectively controls the symptoms of asthma and allergic rhinitis, where montelukast acts by blocking the release of certain chemicals (leukotrienes) in the respiratory tract that triggers the allergic and inflammatory response. It also prevents the narrowing of the airway tract which makes breathing easier.

Quick Suggestions:

• Montelukast should not be used for the relief of acute bronchospasm or as monotherapy for the prevention of exercise-induced bronchospasm. It is not indicated for the reversal of bronchospasm in acute asthma attacks.
• Patients who experience asthma triggered by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should continue to avoid these medications while taking Montelukast.
• Montelukast should not be abruptly substituted for oral or inhaled corticosteroids. If you are currently on corticosteroid therapy, it is important to follow your healthcare provider's instructions regarding the use of Montelukast.
• It is important to be alert for any signs of Churg-Strauss syndrome, a rare condition that can involve eosinophilia (elevated eosinophil levels), vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy. If you experience any of these symptoms, notify your physician.
• Montelukast's use during pregnancy and lactation is not fully established. It is unknown whether the medication is excreted in breast milk, so caution should be exercised when using Montelukast while breastfeeding.
• Montelukast is not recommended for use in children under 6 months of age.

Indication of Odmon 10mg Tablet

• Asthma is a respiratory condition characterized by the narrowing of the airways and excessive mucus production. Odmon 10mg Tablet is prescribed as part of the treatment for asthma, in combination with other medications.
• Allergic rhinitis is an allergic reaction that primarily affects the nose. It can be triggered by various allergens such as dust, pollution, or certain food items. Odmon 10mg Tablet is used to alleviate the symptoms of allergic rhinitis, including a runny nose, watery eyes, sneezing, and itching in the eyes, nose, mouth, or throat.
• Exercise-induced bronchospasm refers to the tightening of the airways during physical exertion, leading to difficulty in breathing. Odmon 10mg Tablet is employed to prevent bronchospasm that can occur during exercise, helping to maintain smooth airflow.

Odmon 10mg Tablet is primarily prescribed to prevent and manage the symptoms associated with asthma, which involve the narrowing of the airways. It is also effective in preventing breathing difficulties that may occur during exercise. Additionally, Odmon 10mg Tablet provides relief from allergy symptoms, including watery eyes, sneezing, difficulty in breathing, and chest tightness. The medication functions by inhibiting the narrowing of the windpipe, thus alleviating allergic symptoms.

Pharmacology

Montelukast is a specific and orally active leukotriene receptor antagonist. It specifically inhibits the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are produced through the metabolism of arachidonic acid and are released from various cells, including mast cells and eosinophils. The binding of cysteinyl leukotrienes to their receptors and the activation of these receptors have been implicated in the pathophysiology of asthma and allergic rhinitis. This includes processes such as airway edema, smooth muscle contraction, and altered cellular activity associated with inflammation. These mechanisms contribute to the signs and symptoms of asthma and allergic rhinitis. By blocking the action of leukotrienes, montelukast helps alleviate these symptoms and improve the management of asthma and allergic rhinitis.

Dosage of Odmon 10mg Tablet

The dosage information for Montelukast. Here's a summary of the adult and child doses:

Adult Dose:

• Chronic asthma: 10 mg as a film-coated tablet once daily in the evening.
• Allergic rhinitis: 10 mg once daily.
• Prophylaxis of exercise-induced asthma: 10 mg at least 2 hours prior to exercise. Do not take additional doses within 24 hours.
• Elderly: No dosage adjustment is needed.
• Mild to moderate hepatic impairment: No dosage adjustment needed.

Child Dose:

• Asthma prophylaxis and maintenance treatment:
  • <12 months: Safety and efficacy not established.
  • 12-24 months: 4 mg (granules) once daily in the evening.
  • 2-6 years: 4 mg (chewable tablet or granules) once daily in the evening.
  • 6-15 years: 5 mg (chewable tablet) once daily in the evening.

15 years: 10 mg (conventional tablet) once daily in the evening.

• Prophylaxis of exercise-induced bronchospasm:
  • 6-15 years: 5 mg (chewable tablet) 2 hours before exercise. Do not take an additional dose within 24 hours.

15 years: 10 mg 2 hours before exercise. Do not take additional dose within 24 hours.

• Perennial allergic rhinitis:
  • <6 months: Safety and efficacy not established.
  • 6-24 months: 4 mg (granules) once daily.
  • 2-6 years: 4 mg (chewable tablet or granules) once daily.
  • 6-15 years: 5 mg (chewable tablet) once daily.

15 years: 10 mg (conventional tablet) once daily.

• Seasonal allergic rhinitis:
  • <2 years: Safety and efficacy not established.
  • 2-6 years: 5 mg (chewable tablet) or 4 mg (granules) once daily.
  • 6-15 years: 5 mg (chewable tablet) once daily.

15 years: 10 mg (conventional tablet) once daily.

Renal Dose:

• No dosage adjustment is needed for renal impairment.

Please note that this is a summary and it's important to follow the specific dosage instructions provided by your doctor or healthcare provider.

Administration of Odmon 10mg Tablet

It's important to follow your physician's advice when taking Odmon 10mg Tablet. Here are the key points to remember:

• Take the tablet as prescribed by your physician.
• Swallow the tablet with a glass of water. Do not crush or chew it.
• You can take the tablet with or without meals.
• The dose, duration of therapy, and frequency of doses will be determined by your doctor based on factors such as your age, body weight, and the specific condition being treated.
• It's important not to stop taking Odmon 10mg Tablet abruptly once your symptoms improve without consulting your doctor.

Remember to always follow your doctor's instructions and reach out to them if you have any concerns or questions regarding your medication.

Interaction

Montelukast has been found to be generally well-tolerated when administered with other therapies used in the prophylaxis and chronic treatment of asthma. There is no significant increase in adverse reactions when Montelukast is used in combination with these therapies.

In terms of drug interactions, it's worth noting that Montelukast is metabolized by cytochrome P-450 enzymes, specifically CYP2C8 and CYP3A4. While the hepatic metabolism of Montelukast can be induced by substances like Phenobarbital or Rifampin, no dosage adjustment is recommended for Montelukast in these cases.

However, it is advisable to monitor patients closely when potent cytochrome P-450 enzyme inducers are co-administered with Montelukast. This is to ensure the effectiveness and safety of both medications and to make any necessary adjustments in the treatment plan if needed.

If you have any specific concerns about potential drug interactions with Montelukast or if you are taking any other medications, it's important to discuss them with your healthcare provider for personalized advice and guidance.

Contraindications

Montelukast is contraindicated for patients with hypersensitivity to any component of this product.

Pregnancy & Lactation

Pregnancy: 

• There are no adequate and well-controlled studies of Montelukast in pregnant women. Because animal reproductive studies are not always predictive of human response, so Montelukast should be used during pregnancy only if clearly needed.

Lactation: 

• It is not known if Montelukast is excreted in human milk, so caution should be exercised when Montelukast is given to a nursing mother.

Precautions & Warnings

• Montelukast should not be used for the relief of acute bronchospasm or as monotherapy for the prevention of exercise-induced bronchospasm. It is not indicated for the reversal of bronchospasm in acute asthma attacks.
• Patients who experience asthma triggered by aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should continue to avoid these medications while taking Montelukast.
• Montelukast should not be abruptly substituted for oral or inhaled corticosteroids. If you are currently on corticosteroid therapy, it is important to follow your healthcare provider's instructions regarding the use of Montelukast.
• It is important to be alert for any signs of Churg-Strauss syndrome, a rare condition that can involve eosinophilia (elevated eosinophil levels), vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy. If you experience any of these symptoms, notify your physician.
• Montelukast's use during pregnancy and lactation is not fully established. It is unknown whether the medication is excreted in breast milk, so caution should be exercised when using Montelukast while breastfeeding.
• Montelukast is not recommended for use in children under 6 months of age.

Storage Conditions

Keep away from light and heat in a dry location. Keep out of children's reach.