Arofil SR (Theophylline) is indicated for:
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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush, or break it. Arofil 400 SR is to be taken with food.
Arofil 400 SR is a bronchodilator. It works by relaxing the muscles of the airways and widening the airways. This makes breathing easier.
Arofil 400 SR is used to treat and prevent symptoms of asthma and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lung is blocked).
Theophylline is a bronchodilator belonging to the Methylxanthine class. It relaxes smooth muscles in the airways and suppresses the airway's response to stimuli, making it useful in treating conditions like asthma and COPD. Theophylline also enhances diaphragmatic muscle contraction, improving breathing in patients. The half-life of Theophylline varies between 3 to 9 hours, depending on several factors, such as smoking, age, and co-existing conditions.
Recommended Maintenance Dosage:
The dose of Theophylline is individualized based on peak serum Theophylline concentration to balance effectiveness and minimize adverse effects. Sustained-release formulations are usually administered every 12 hours in adults, though children may require dosing every 8 hours due to faster metabolism.
Avoid concurrent use with xanthine derivatives.
Drugs that increase the clearance of Arofil SR:
Hypokalemia risk: Arofil SR can worsen hypokalemia when used with beta-2-agonists, steroids, diuretics, and during hypoxia. Serum potassium levels should be monitored in such cases.
Hypersensitivity to Theophylline or any component of Arofil SR.
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