Reconil 200mg Tablet

✔️ Uses of Reconil 200mg Tablet

• Rheumatoid arthritis
• Systemic lupus erythematosus (SLE)

✔️ How does Reconil 200mg Tablet work?

Reconil is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It suppresses the overactivity of the immune system, reducing inflammation and pain in the joints.

✔️ Side Effects of Reconil 200mg Tablet

Retinopathy, hair loss, photosensitivity, tinnitus, myopathy. Psychosis, seizures, leucopenia, aplastic anemia, hepatitis, GI upsets, dizziness, hypokalemia, headache, pruritus, urticaria.

✔️ Quick Suggestions:

• Take as prescribed for autoimmune conditions.
• Have regular eye tests while on this medication.
• Inform your doctor if you experience hypoglycemia symptoms.

✔️ Indication

Hydroxychloroquine is used in the treatment of Rheumatoid arthritis, systemic lupus erythematosus, and type 2 diabetes mellitus.

✔️ Pharmacology

Hydroxychloroquine Sulphate is a synthetic form of quinine. It suppresses the immune system by decreasing the generation of rheumatoid and acute phase reactants. It also accumulates in white blood cells, where it stabilizes lysosomal membranes and inhibits the function of several enzymes, including collagenase and the proteases that break down cartilage. It also kills growing parasites by breaking the cell walls of infected red blood cells.

✔️ Dosage & Administration of Reconil 200mg Tablet

• Rheumatoid Arthritis: 400-600 mg daily
• Systemic Lupus Erythematosus: 400 mg once or twice daily
• Malaria (Acute treatment): 800 mg initially, then 400 mg at 6-8 hours, 400 mg at 24 and 48 hours
• Malaria (Prophylaxis): 400 mg weekly, starting 2 weeks before exposure, continued for 4 weeks after departure
• Take it with food. If you miss a dose, take it as soon as possible. Do not double the dose if it's almost time for the next one.

✔️ Interaction

• Cimetidine may increase serum levels
• Absorption may be decreased by kaolin or Mg trisilicate
• Avoid digoxin and alcohol
• Increased risk of ventricular arrhythmias with halofantrine
• Increased risk of convulsions with mefloquine

✔️ Contraindications

• Retinal or visual changes due to any 4-aminoquinoline compound
• Hypersensitivity to 4-aminoquinoline compounds
• Long-term therapy in children

✔️ Pregnancy & Lactation

• Take during pregnancy only if necessary
• If detected in minute levels in breast milk, consult with the doctor before use

✔️ Precautions & Warnings

• Impaired liver or renal function
• Severe GI disorders, porphyria, psoriasis, neurological disorders
• Monitor CBC in patients with prolonged therapy
• Highly toxic to children
• An ophthalmologic checkup is required every 12 months

✔️ Storage Conditions

Store below 30°C, protected from light & moisture. Keep all medicines out of reach of children.