Revofer 500mg/10ml Injection

Uses of Revofer 500mg/10ml Injection

Iron deficiency anemia.

How does Revofer 500mg/10ml Injection work?

Revofer 500mg/10ml Injection contains iron in the form of Ferric carboxymaltose. Iron is an essential micronutrient that gives the red blood cells a reddish-brown color and the capacity to transport oxygen. It improves oxygen levels in the body and corrects tiredness, weakness, and shortness of breath caused due to anemia.

Side Effects of Revofer 500mg/10ml Injection

• Common: Nausea, hypertension, flushing, dizziness, vomiting, pruritus, rash, urticaria, wheezing, injection site discoloration, headache.
• Serious anaphylactic/anaphylactoid reactions are reported rarely.

Quick Suggestions:

• Revofer is an iron replacement medication used for iron deficiency anemia.
• Administered via injection or infusion under medical supervision.
• Common side effects include injection site reactions, nausea, vomiting, headache, and dizziness.
• Not suitable if anemia is not caused by iron deficiency.
• Inform your doctor about existing medical conditions before treatment.
• Tests will be conducted to monitor blood cells, iron levels, and treatment progress.

Indications:

Anaemia occurs when your body lacks enough red blood cells to effectively transport oxygen. Insufficient iron intake, either due to poor nutrition or absorption issues, can lead to decreased red blood cell production and anemia. Revofer 500mg/10ml Injection is an iron replacement product designed to address this deficiency.

By boosting red blood cell levels, Revofer can alleviate symptoms of anemia such as fatigue and weakness. Typically administered by a doctor or nurse via injection, the treatment regimen often involves two doses spaced 7 days apart. It's crucial to attend all scheduled appointments for optimal management of your condition.

However, it's important to note that Revofer should not be used if your anemia is not caused by iron deficiency. Always follow your healthcare provider's recommendations regarding treatment options for your specific condition.

Pharmacology

Revofer is a colloidal iron (III) hydroxide complexed with Carboxymaltose, a Carbohydrate polymer releasing iron.

Dosage & Administration:

IV Preparation:

• For IV infusion, dilute Revofer in up to 250 mL 0.9% NaCl.
• The resulting concentration should be >2 mg/mL.

IV Administration:

• IV push: May administer undiluted at a rate of 100 mg/minute.
• IV infusion: Dilute the dose in up to 250 mL 0.9% NaCl and infuse over at least 15 minutes.

Injection for Iron-deficiency Anemia:

• Indicated for adults with intolerance or unsatisfactory response to oral iron, or with non-dialysis dependent chronic kidney disease.
• For adults >50 kg: Administer 750 mg IV once, followed by a second 750 mg dose after 7 days; cumulative dose not to exceed 1500 mg per course.
• For adults <50 kg: Administer 15 mg/kg IV once, followed by a second dose after 7 days; cumulative dose not to exceed 1500 mg per course.

Intravenous preparation and administration.

• Administered by a healthcare professional; do not self-administer.
• Follow up with your doctor if a dose is missed.
• Excessive dosages may lead to iron accumulation; monitor iron parameters.
• Treat iron accumulation according to standard medical practice.

Interaction

Formal drug interaction studies were not conducted.

Contraindications

• Hypersensitivity to active substances or any excipients.
• Serious hypersensitivity to other parenteral iron products.
• Anemia is not attributed to iron deficiency.
• Evidence of iron overload or disturbances in iron utilization.

Pregnancy & Lactation

• Use during pregnancy requires careful benefit/risk evaluation. Avoid unless necessary.
• Limited data on breastfeeding suggest low risk to the infant.

Precautions & Warnings

• Serious hypersensitivity reactions were reported; monitor for signs during and after administration.
• Transient elevations in blood pressure may occur; monitor for hypertension.
• Laboratory tests may overestimate serum iron and transferrin-bound iron.
• Special caution in patients with chronic kidney disease and pediatric population under 14 years.
• Limited data on breastfeeding suggest minimal risk to the infant.

Storage Conditions:

Store below 30°C, in a dry place, away from light. Do not freeze. Keep out of reach of children.