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Pregabalin is used in adults to treat:
- Peripheral and central neuropathic pain
- Epilepsy (fits or seizures) in combination with other medicines
- Generalized Anxiety Disorder
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✅ Description:
Neugalin 25mg Capsule contains Pregabalin, belonging to the Anticonvulsant group. It is utilized in adults to address neuropathic pain, specific forms of epilepsy, and anxiety disorders.
Neuropathic Pain: Long-lasting pain resulting from damaged nerve fibers characterized by sensations like burning, stabbing, tingling, or numbness. It may also impact mood, and sleep, and cause fatigue.
Epilepsy Treatment: Neugalin 25mg Capsule can be used to treat certain forms of epilepsy, working in conjunction with other anti-epileptic medications.
Generalized Anxiety Disorders: Effective in treating severe anxiety affecting daily activities when other medications are ineffective.
Pregabalin controls seizures by reducing abnormal nerve cell activity in the brain. It diminishes pain sensations by blocking the transmission of pain signals through the nervous system. Additionally, it alleviates anxiety by reducing the release of specific brain chemicals causing abnormal mood stimulation and anxiety.
Before taking Neugalin 25mg Capsule, inform your doctor about lung, liver, kidney, or heart problems. Disclose any history of diabetes, other nerve or brain disorders, or drug abuse.
Safety Advices
Alcohol
UNSAFE
Avoid consumption of alcohol while taking Neugalin 25mg Capsule as it could aggravate your dizziness.
Pregnancy
CONSULT YOUR DOCTOR
Neugalin 25mg CapsuleSULE is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of childbearing age must use a suitable contraceptive method (non-hormonal methods) to avoid pregnancy while undergoing therapy with Neugalin 25mg Capsule
Breastfeeding
CONSULT YOUR DOCTOR
Neugalin 25mg Capsule is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
Driving
UNSAFE
Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking Neugalin 25mg Capsule.
Kidney
CONSULT YOUR DOCTOR
Neugalin 25mg Capsule should be used with caution in patients with kidney diseases (such as decreased urination). Therefore, consult your doctor before taking it.
Liver
CAUTION
Neugalin 25mg Capsule should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.
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✔️ Uses:
Treatment of
- Neuropathic pain
- Epilepsy/Seizures
- Fibromyalgia
✔️ How does Neugalin 25mg Capsule work?
Its mechanism of action involves reducing abnormal electrical activity in the brain, and preventing seizures. Additionally, it is employed to alleviate nerve and muscle pain by interfering with pain signals within damaged nerves and the brain.
✔️ Side Effects of Neugalin 25mg Capsule
Common adverse effects include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, and aberrant thinking.
✔️ Quick Suggestions:
- Avoid alcohol, as it may intensify dizziness, increasing the risk of injuries, falls, or accidents.
- Do not use Neugalin 25mg Capsule without consulting your doctor if pregnant or breastfeeding. Women of childbearing age should use suitable contraceptives to prevent pregnancy during therapy.
- Exercise caution in elderly patients, particularly those with kidney problems.
- Regularly monitor blood sugar levels, as Neugalin 25mg Capsule may alter them.
- It may cause weight gain, particularly in diabetic patients. Consult your doctor if it becomes bothersome.
✔️ Indications:
- Management of neuropathic pain associated with diabetic peripheral neuropathy.
- Management of post-herpetic neuralgia.
- Adjunctive therapy for adult patients with partial onset seizures.
- Management of fibromyalgia.
- Neuropathic pain associated with spinal cord injury.
✔️ Pharmacology
Pregabalin, a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), exhibits high affinity to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. With an oral bioavailability of ≥90%, it is eliminated from the systemic circulation primarily through renal excretion. The elimination half-life is approximately 6.3 hours in subjects with normal renal function.
✔️ Dosage & Administration of Neugalin 25mg Capsule
- Neuropathic pain associated with diabetic peripheral neuropathy: Start at 50 mg three times a day, may increase to 300 mg/day.
- Post-herpetic neuralgia: Initiate at 75 mg two times a day, may increase to 300 mg/day.
- Adjunctive therapy for partial-onset seizures: The recommended maximum dose is 600 mg/day.
- Management of fibromyalgia: Begin with 75 mg two times a day, may increase to 300 mg/day.
- Neuropathic pain associated with spinal cord injury: Recommended dose range is 150 to 600 mg/day.
✔️ Interaction
Pregabalin shows no significant interactions with other antiepileptic drugs or oral contraceptives. Ethanol and lorazepam effects may be potentiated by pregabalin.
✔️ Contraindications
Avoid in patients with known hypersensitivity to pregabalin or its components.
✔️ Pregnancy & Lactation
Category C; use during pregnancy only if benefits outweigh risks. Passes into breast milk; use in nursing mothers if benefits outweigh risks.
✔️ Precautions & Warnings
Withdraw gradually to avoid insomnia, nausea, headaches, and diarrhea. Monitor creatinine kinase levels, and discontinue if myopathy is suspected.
✔️ Storage Conditions
Store below 30°C, protected from light and moisture. Keep out of reach of children.
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