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Tirzep 5 Sterile Solution For Injection
Tirzep is prescribed to improve blood sugar control in adults with type 2 diabetes in combination with a healthy diet and regular exercise.
- It has not been tested in people with a history of pancreatitis.
- It is not meant for patients with type 1 diabetes.
Not approved for use in individuals under 18 years old
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✅ Description:
Tirzepatide is a dual receptor agonist that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. It's a modified 39-amino-acid peptide with a fatty acid chain (C20) that allows for albumin binding, extending its duration of action.
Mechanism of action:
- Stimulates insulin secretion (both first and second phases)
- Lowers glucagon levels, both in a glucose-dependent way
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses
- To improve glycemic control in adults with Type 2 diabetes mellitus
- Management of Obesity
✔️ Side Effects
Nausea, vomiting, diarrhea, constipation, reduced appetite, indigestion, abdominal discomfort
✔️ Dosage & Administration
Dosing Guidelines:
- Start with 2.5 mg once weekly for the first 4 weeks (not for blood sugar control)
- Increase to 5 mg once weekly
- If needed, increase by 2.5 mg every 4 weeks based on response
Maximum dose: 15 mg once weekly
Missed dose:
- Take it within 4 days (96 hours) of the missed dose
- If more than 4 days have passed, skip it and return to the regular schedule
Changing dosing day: Must allow at least 72
✔️ Preparation & Administration Instructions
- Do not freeze or use if frozen
- Protect from light
- Inspect visually for particles or discoloration before use
- Inject into abdomen, thigh, or upper arm; rotate sites with each dose
- When using with insulin, do not mix; inject at different sites
Note: The prefilled syringe contains natural rubber (latex derivative), which may cause allergic reactions.
✔️ Do not use Tirzep if:
- You’re allergic to tirzepatide or any ingredient in the product
- You or a family member has a history of medullary thyroid carcinoma (MTC)
- You have multiple endocrine neoplasia syndrome type 2 (MEN 2)
✔️ Medications That May Interact
Includes, but is not limited to:
- Alcohol
- Aspirin, NSAIDs
- Blood pressure/heart medications (beta blockers, diuretics, etc.)
- Medications for HIV/AIDS
- Hormones (estrogen, testosterone, thyroid hormones)
- Antibiotics, antivirals, antifungals
- Other diabetes meds (sulfonylureas, insulin)
- Antidepressants, MAOIs, and mental health medications
- Herbal supplements and weight loss medications
✔️ Pregnancy & Lactation
- Should be used during pregnancy only if needed
- Consider risks of poorly controlled diabetes to both mother and baby
- During breastfeeding, weigh the benefits against potential risks to the infant
✔️ Precautions
- Warn patients about the potential for thyroid tumors (especially MTC)
- Monitor for pancreatitis; discontinue if suspected
- Monitor kidney function in patients with GI side effects
- Watch for progression of diabetic retinopathy
- Evaluate for gallbladder issues if symptoms occur
- Discontinue immediately if severe allergic or hypersensitivity reactions develop
✔️ Storage
- Store in the refrigerator at 2°C to 8°C
- Keep away from light
- Do not freeze
- Keep out of reach of children
- Use only on the prescription of a licensed physician
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
