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Tirzep 5 Sterile Solution For Injection
Tirzep is prescribed to improve blood sugar control in adults with type 2 diabetes in combination with a healthy diet and regular exercise.
- It has not been tested in people with a history of pancreatitis.
- It is not meant for patients with type 1 diabetes.
Not approved for use in individuals under 18 years old
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✅ Description:
Tirzepatide is a dual receptor agonist that activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. It's a modified 39-amino-acid peptide with a fatty acid chain (C20) that allows for albumin binding, extending its duration of action.
Mechanism of action:
- Stimulates insulin secretion (both first and second phases)
- Lowers glucagon levels, both in a glucose-dependent way
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses
- To improve glycemic control in adults with Type 2 diabetes mellitus
- Management of Obesity
✔️ Side Effects
Nausea, vomiting, diarrhea, constipation, reduced appetite, indigestion, abdominal discomfort
✔️ Dosage & Administration
Dosing Guidelines:
- Start with 2.5 mg once weekly for the first 4 weeks (not for blood sugar control)
- Increase to 5 mg once weekly
- If needed, increase by 2.5 mg every 4 weeks based on response
Maximum dose: 15 mg once weekly
Missed dose:
- Take it within 4 days (96 hours) of the missed dose
- If more than 4 days have passed, skip it and return to the regular schedule
Changing dosing day: Must allow at least 72
✔️ Preparation & Administration Instructions
- Do not freeze or use if frozen
- Protect from light
- Inspect visually for particles or discoloration before use
- Inject into abdomen, thigh, or upper arm; rotate sites with each dose
- When using with insulin, do not mix; inject at different sites
Note: The prefilled syringe contains natural rubber (latex derivative), which may cause allergic reactions.
✔️ Do not use Tirzep if:
- You’re allergic to tirzepatide or any ingredient in the product
- You or a family member has a history of medullary thyroid carcinoma (MTC)
- You have multiple endocrine neoplasia syndrome type 2 (MEN 2)
✔️ Medications That May Interact
Includes, but is not limited to:
- Alcohol
- Aspirin, NSAIDs
- Blood pressure/heart medications (beta blockers, diuretics, etc.)
- Medications for HIV/AIDS
- Hormones (estrogen, testosterone, thyroid hormones)
- Antibiotics, antivirals, antifungals
- Other diabetes meds (sulfonylureas, insulin)
- Antidepressants, MAOIs, and mental health medications
- Herbal supplements and weight loss medications
✔️ Pregnancy & Lactation
- Should be used during pregnancy only if needed
- Consider risks of poorly controlled diabetes to both mother and baby
- During breastfeeding, weigh the benefits against potential risks to the infant
✔️ Precautions
- Warn patients about the potential for thyroid tumors (especially MTC)
- Monitor for pancreatitis; discontinue if suspected
- Monitor kidney function in patients with GI side effects
- Watch for progression of diabetic retinopathy
- Evaluate for gallbladder issues if symptoms occur
- Discontinue immediately if severe allergic or hypersensitivity reactions develop
✔️ Storage
- Store in the refrigerator at 2°C to 8°C
- Keep away from light
- Do not freeze
- Keep out of reach of children
- Use only on the prescription of a licensed physician
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
