Oradin 10mg Tablet

Uses of Oradin10mg Tablet

• Allergic conditions [hay fever, conjunctivitis (red, itchy eyes)
• Eczema
• Hives (urticaria, nettle rash)
• Reactions to insect bites and stings, and some food allergies]

How does Oradin10mg Tablet work?

It treats allergy symptoms such as itching, swelling, and rashes by blocking the effects of a chemical messenger (histamine) in the body.

Side Effects of Oradin10mg Tablet

• Headache
• Fatigue
• Hypotension
• Palpitations
• Tachycardia
• Anxiety
• Depression
• Breast Pain
• Pharyngitis

Quick Suggestions:

• Your doctor has prescribed Oradin 10mg Tablet to help relieve allergy symptoms such as itching, swelling, and rashes.
• As compared to other similar medications, it is much less likely to make you feel sleepy.
• Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
• Do not drink alcohol while taking this medication as it may cause increased sleepiness.
• Stop taking Oradin 10mg Tablet at least three days before taking an allergy test as it can affect the test results.
• Oradin 10mg Tablet should not be given to children under 12 years of age.
• Patients with underlying medical conditions like liver, kidney disorders, diabetes, convulsions, etc. should consult their treating doctor before consuming Oradin 10mg Tablet.
• Oradin 10mg Tablet should not be given to children under 12 years of age.
• Patients with underlying medical conditions like liver, kidney disorders, diabetes, convulsions, etc. should consult their treating doctor before consuming Oradin 10mg Tablet.

Indication

This drug acts as an antihistamine and is use to treat allergic rhinitis and urticaria.

Pharmacology

Loratadine is an antihistamine and a selective peripheral H1-receptor antagonist. It is commonly used as an antiallergic medication. Loratadine works by blocking the action of histamine, a substance that is released during an allergic reaction. By blocking the H1 receptors, Loratadine helps to reduce the symptoms associated with allergies, such as sneezing, itching, runny nose, and watery eyes.

One of the advantages of Loratadine is its non-sedative nature, meaning it does not typically cause drowsiness or sedation. This makes it a preferred choice for many individuals who need relief from allergy symptoms but want to avoid the side effect of drowsiness that is often associated with older antihistamines. Additionally, Loratadine is considered a long-acting antihistamine, providing relief for up to 24 hours, which allows for once-daily dosing.

Dosage & Administration of Oradin10mg Tablet

• Adults and children over 12 years of age: Take one Loratadine tablet (10mg) once daily. It is typically taken in the morning or when symptoms require treatment.
• Children 2-12 years: For children with a body weight over 30 kg, they should take one Loratadine tablet (10mg) once daily. Children with a body weight below 30 kg, should take half of a Loratadine tablet (5mg) once daily.
• It's worth noting that Loratadine tablets are not recommended for use in children below 2 years of age, as the safety and efficacy of the medication have not been established in this age group.

Remember to swallow the Loratadine tablet whole and not crush or chew it. The specific dosage and duration of treatment will be determined by your doctor, taking into consideration factors such as your age, body weight, and the specific condition being treated. It's important to follow your doctor's instructions and consult them if you have any questions or concerns about the medication.

Interaction

Alcohol: Unlike some other antihistamines, Loratadine does not have potentiating effects when combined with alcohol. However, it's always advisable to use caution when consuming alcohol while taking any medication.

Hepatic Cytochrome P450 Interactions: Medications that inhibit or are processed by hepatic cytochrome P450 3A4 and 2D6 enzymes may affect the plasma concentrations of Loratadine. Cimetidine can inhibit both enzymes, while erythromycin and ketoconazole primarily inhibit cytochrome P450 3A4. Concurrent use of these medications may increase Loratadine levels in the blood, but no significant side effects have been reported.

Other Medications: It's important to discuss with your doctor any other medications, herbal preparations, or supplements you are currently taking. While there have been no reports of potentially dangerous interactions with Loratadine, it's always best to ensure there are no potential interactions that could affect your health or the efficacy of the medications you're taking.

In general, it's recommended to inform your healthcare provider about all the medications you are using, including over-the-counter drugs, herbal products, and supplements, to avoid possible drug interactions. Your doctor can provide personalized advice based on your specific situation and medical history.

Contraindications

If a patient has experienced an allergic reaction or hypersensitivity to Loratadine or any of its ingredients in the past, it is important to avoid using the medication. Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, or difficulty breathing.

In case of any known hypersensitivity or previous adverse reactions to Loratadine, it is crucial to inform your healthcare provider or pharmacist. They can provide alternative treatment options or suggest suitable alternatives based on your individual circumstances.

Pregnancy & Lactation

there is limited evidence regarding the use of Loratadine during pregnancy. Due to the lack of extensive data on its safety in pregnant women, it is generally not recommended to use Loratadine during pregnancy unless specifically advised by a healthcare professional.

Similarly, although Loratadine is excreted in small amounts in breast milk, it is generally not recommended for use by nursing mothers unless prescribed by a doctor. It's important to consider the potential risks and benefits and consult with a healthcare professional before using any medication while breastfeeding.

Pregnant women and nursing mothers should always seek guidance from their healthcare provider before taking any medication to ensure the safety and well-being of themselves and their baby. The healthcare provider can evaluate the individual's specific situation and provide appropriate recommendations or suggest alternative treatment options if necessary.

Precautions & Warnings

Hepatic Disease: Loratadine should be used with caution in patients with hepatic disease. The liver plays a role in the metabolism and elimination of drugs, and impaired liver function can affect the processing of medications. It is advisable to consult a healthcare professional who can assess the individual's specific liver condition and determine the appropriate dose or frequency of Loratadine if needed.

Renal Insufficiency: In patients with renal insufficiency, particularly when the estimated glomerular filtration rate (eGFR) is 30 ml/min or lower, caution should be exercised when using Loratadine. Reduced kidney function can affect the clearance of drugs from the body, potentially leading to higher drug levels in the bloodstream. Your healthcare provider can determine the appropriate dose adjustment or frequency of administration based on the degree of renal impairment.

Storage Conditions

• Store this medicine below 25°C in a cool and dry place.
• Protect it from light and moisture.
• Keep it out of the reach and sight of children and pets.