Flucloxin contains Flucloxacillin, a penicillinase-resistant beta-lactam antibiotic with high activity against Gram-positive organisms. It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death.
Flucloxacillin effectively blocks the action of transpeptidase, a crucial enzyme in the final stage of peptidoglycan cross-linking, which provides strength and stability to the bacterial cell wall. Due to its unique acyl side chain, the drug resists destruction by penicillinase enzymes.
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Flucloxin is indicated for the treatment of a wide range of Gram-positive bacterial infections, especially those caused by penicillinase-producing staphylococci.
Boils, abscesses, carbuncles
Infected skin conditions (ulcers, eczema, acne, furunculosis)
Cellulitis, infected wounds, burns
Otitis media & externa
Impetigo
Pneumonia, lung abscess, empyema
Sinusitis, pharyngitis, tonsillitis, quinsy
Osteomyelitis, enteritis, endocarditis
Urinary tract infections, meningitis, septicemia
Used preventively in major surgeries such as orthopedic and cardiothoracic procedures.
Adults: 250 mg four times daily; up to 8 g/day in severe infections
Children 2–10 years: Half of the adult dose
Children under 2 years: One-fourth of the adult dose
✅ Take 1 hour before meals
Known hypersensitivity to penicillins or Flucloxacillin
Pregnancy: Category B – use only when clearly needed
Lactation: Excreted in breast milk; use with caution in nursing mothers
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