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Type: Cream Generic Name:Betamethasone valerate O. 1% & neomycin sulphate 0.5%: cream. Manufacturer/Distributor: Opsonin
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✅ Description:
Indications of Betson-CL Cream
This topical preparation is indicated for the topical treatment of inflammatory dermal infections like-
Tinea pedis
Tinea cruris
Tinea corporis etc.
Pharmacology of Betson-CL Cream
Clotrimazole is a broad-spectrum antifungal drug that is used to treat infections caused by pathogenic dermatophytes, yeasts, and Malassezia furfur. Inhibition of the formation of ergosterol, a key sterol in the fungal cell membrane, is the mechanism of action. As a result, the cell membrane becomes unstable, and the fungus eventually dies. Betamethasone dipropionate is an anti-inflammatory, anti-pruritic, and vasoconstrictive corticosteroid. However, the precise mechanism of action of corticosteroids remains unknown.
Dosage & Administration of Betson-CL Cream
Sufficient topical preparation should be applied onto the affected and surrounding skin areas twice a day, in the morning and evening, for 2 weeks in tinea cruris and tinea corporis and for 4 weeks in tinea pedis. The use of this cream for longer than four weeks is not recommended.
The safety and effectiveness of the preparation have not been established in children below the age of 12 years.
Contraindications
Patients who are allergic to any of the ingredients in this topical solution, as well as other corticosteroids or imidazoles, should avoid using it. If irritation or sensitization occurs as a result of using the cream, treatment should be stopped and proper therapy started. Facial rosacea, acne vulgaris, perioral dermatits, perianal and vaginal pruritus, napkin eruptions, and bacterial or viral infections are all contraindications to using the cream. Topical corticosteroids can cause reversible inhibition of the hypothalmic-pituitary-adrenal (HPA) axis when absorbed systemically. If HPA axis suppression is observed, the medicine should be discontinued or the frequency of application reduced.
Side Effects of Betson-CL Cream
Paresthesia was recorded in 1.9 percent of patients in clinical trials, followed by rash, edema, and secondary infection, all of which occurred in less than 1% of patients. Other side effects of the medication included scorching and dry skin in 1.6 percent of patients and stinging in less than 1% of individuals.
Pregnancy & Lactation
In pregnancy, there is insufficient proof of safety. Clotrimazole is not teratogenic in animals, although it is foetotoxic at high dosages. Corticosteroids used topically in pregnant animals can cause fetal development problems. As a result, the cream should only be used during pregnancy if the benefit outweighs the danger to the fetus, and it should not be used in large amounts or for lengthy periods of time. Because it is unknown whether the preparation's components are excreted in human milk, caution should be used when treating nursing women.
Storage Conditions
Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.
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