Nevan 0.1% Eye Drops 5ml

Nepafenac is a nonsteroidal anti-inflammatory prodrug (NSAID). After instillation in the eye, it penetrates the cornea and is converted by ocular tissue hydrolase to Amfenac, a potent nonsteroidal anti-inflammatory drug. Amfenac is thought to inhibit the action of the cyclooxygenase enzyme. This enzyme is required for prostaglandin synthesis.

Nepafenac 0.1% Sterile Ophthalmic Suspension-

• For post-operative pain & inflammation: Instill 1 drop 3 times daily 1 day before cataract surgery and continue on the day of surgery and through the first 2 weeks of the post-operative period.
• For surgery-induced miosis: Instill 1 drop 3 times daily 1 day before surgery & on the day of surgery.
• For prevention of post-operative CME: Instill 1 drop 3 times daily 1 day before surgery and continue on the day of surgery and through the first 6 weeks of the post-operative period.

Nepafenac 0.3% Sterile Ophthalmic Suspension-

• For post-operative pain & inflammation: Instill 1 drop once daily 1 day before cataract surgery and continue on the day of surgery and through the first 2 weeks of the post-operative period. An additional drop should be administered 30 to 120 minutes before surgery.

Contraindicated in patients with previously demonstrated hypersensitivity to any of the ingredients in the formulation or to other NSAIDs.

Reported side effects are foreign body sensation, lid margin crusting, ocular discomfort, ocular hyperemia, etc.

Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Nepafenac should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Use in lactation: It is not known whether this drug is excreted in human milk. So, caution should be exercised when Nepafenac ophthalmic suspension is administered to a nursing mother.

Nevan should be used with caution in patients with known bleeding tendencies or who are receiving medications which may prolong bleeding time.

• Keep Nevan out of reach of children
• Store Nevan at room temperature