Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID). After instillation into the eye, it penetrates the cornea and is converted by ocular tissue hydrolase into amfenac, its active metabolite. Amfenac exerts its effect by inhibiting the cyclooxygenase (COX) enzyme, which is essential for prostaglandin synthesis, thereby reducing inflammation and pain.
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Optafenac 0.1% Sterile Ophthalmic Suspension is indicated for the treatment of post-operative ocular pain and inflammation, including after cataract surgery. It is also used for the prevention of surgery-induced miosis and for reducing the risk of post-operative cystoid macular edema (CME).
Optafenac 0.3% Sterile Ophthalmic Suspension is indicated for the management of post-operative pain and inflammation associated with cataract surgery.
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Nepafenac is contraindicated in patients with:
Possible adverse effects include:
Pregnancy:
There are no adequate and well-controlled studies in pregnant women. Nepafenac should be used during pregnancy only if the expected benefit justifies the potential risk to the fetus.Lactation:
It is unknown whether the drug is excreted in human breast milk. Caution should be exercised when administering to breastfeeding mothers.
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