Vitilen 10mg Capsule

✔️ Dosage & Administration For Vitiligo

Vitiligo

• Take 20 mg (two 10 mg capsules) in a single dose with milk or food, 2–4 hours before exposure to UVA light or sunlight.
• Treatment should be given on alternate days only, never on two consecutive days.

Suggested sunlight exposure schedule:

Further exposure should be increased gradually depending on skin response, redness, and tenderness.

✔️ Dosage & Administration For Psoriasis

Psoriasis

Capsules should be taken 2 hours before UVA exposure with food or milk.

✔️ Side Effects

The most commonly reported adverse effect is nausea, affecting approximately 10% of patients. Taking the medication with food or milk may help reduce this effect.

Other possible side effects include:

• Nervousness
• Difficulty sleeping (insomnia)
• Mood changes or depression

✔️ Methoxsalen Lotion

The lotion should be applied by a healthcare professional to clearly defined vitiligo patches, followed by controlled UVA exposure. Initial exposure should be conservative and generally not exceed half of the minimal erythema dose. Treatments are usually given once weekly or less frequently, depending on the patient’s response.

Visible pigmentation may begin within a few weeks, but significant improvement often requires 6–9 months of treatment. Maintenance therapy may be necessary to preserve newly developed pigmentation.

Pediatric Use: Safety and effectiveness in children have not been established.

Administration Precautions

Individuals applying the lotion should wear gloves or finger protection to prevent accidental photosensitization and skin burns.

✔️ Overdose

In the event of an overdose, vomiting may be induced if appropriate, and the patient should remain in a dark environment for at least 24 hours to minimize the risk of severe photosensitivity reactions. This measure is most effective within the first few hours after ingestion.

✔️ Pregnancy & Lactation

Pregnancy: Classified as Pregnancy Category C. It should be used during pregnancy only if the potential benefits outweigh the possible risks.

Breastfeeding: It is unknown whether Methoxsalen passes into breast milk. Caution is advised when administering the medication to nursing mothers.

✔️ Precautions & Warnings

• Skin Burns: Severe burns may occur if recommended UVA or sunlight exposure guidelines are not strictly followed.
• Skin Cancer Risk: Long-term PUVA therapy may increase the risk of skin cancer, particularly in fair-skinned individuals or those with previous exposure to UV radiation, tar treatments, ionizing radiation, or arsenic.
• Eye Protection: Proper eye protection should be used during PUVA therapy to reduce the risk of cataracts.
• Patients should avoid sunbathing during the 24 hours before taking Vitilen and undergoing UV exposure.

✔️ Storage Condition

Store below 30°C, protected from light and moisture. Keep out of reach of children.