Mesagut 400 Tablet is used as a treatment for inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease.
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Mesagut may be prescribed for:
Mesagut contains mesalazine (also known as mesalamine), an anti-inflammatory medicine belonging to the aminosalicylate group. It is used to treat inflammatory bowel disease (IBD), particularly ulcerative colitis, by reducing inflammation in the lining of the intestine.
Depending on the formulation and approved indication, mesalazine may be prescribed to manage active disease and help maintain remission.
The dose depends on the condition being treated, disease severity, age, kidney function, and the formulation prescribed.
Treatment of active mild-to-moderate ulcerative colitis in adults
A commonly used regimen for certain 400 mg formulations is 800 mg three times daily.
Depending on the specific product and clinical response, the total daily dose may be increased under medical supervision.
Maintenance of ulcerative colitis remission in adults
The dose is individualized according to the formulation and the patient's response. A regimen of 1.6 g daily is listed in the supplied source for a particular tablet regimen.
Children
Paediatric doses must be calculated and prescribed by a specialist according to the child's age, weight, condition, and specific formulation.
Mesalazine acts primarily on the intestinal lining, where it helps reduce inflammation. It affects inflammatory pathways involved in the production of prostaglandins and other inflammatory substances, helping relieve inflammation associated with inflammatory bowel disease.
Pregnancy: Mesagut should be used during pregnancy only after a doctor has assessed the potential benefits and risks.
Breastfeeding: Consult your doctor before use. The decision depends on the clinical need and the potential risks to the infant.
NSAIDs, such as ibuprofen or naproxen, which may increase concern about kidney-related adverse effects when used with mesalazine.
Azathioprine, which may increase the risk of certain blood-related adverse effects and requires appropriate monitoring.
Do not start or stop other medicines without consulting your healthcare professional.
Mesagut should not be used by people with a known hypersensitivity to mesalazine, salicylates, or any component of the prescribed formulation. Check the product-specific prescribing information for any additional contraindications.
Store below 30°C, protected from light and moisture. Keep all medicines out of the reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.