Mesacol Suppository 7pcs

Uses:

• Treats and prevents mild-to-moderate Ulcerative colitis

How to Use Mesacol Suppository

Suppository:

• Empty bowels if necessary.
• Wash hands thoroughly.
• Lie on the left side, and raise the right knee to the chest.
• Remove the wrapper, and insert the suppository into the rectum.
• Grease the suppository tip if needed.

Side Effects of Mesacol Suppository

• Nausea
• Vomiting
• Diarrhea
• Stomach pain, indigestion
• Headaches
• Muscle aches

Quick Suggestions:

• You have been prescribed Mesalazine for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
• Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
• Do not take Mesalazine if you are allergic to aspirin or if you have blood disorders.
• Do not stop taking the medication suddenly without talking to your doctor.

Indication

Mesacol Suppository contains Mesalamine, an anti-inflammatory agent used to treat and prevent mild-to-moderate Ulcerative colitis. This inflammatory bowel disease causes swelling and inflammation in the bowel, colon, and rectum, leading to symptoms like rectal bleeding, stomach pain, and bloody diarrhea.

Pharmacology

Pharmacologically, mesalazine (also known as mesalamine) acts as an anti-inflammatory agent. It belongs to the class of medications called aminosalicylates. The exact mechanism of action of mesalazine in treating inflammatory bowel diseases like ulcerative colitis is not fully understood, but it is believed to involve several processes.

Inhibiting Prostaglandin Production: Prostaglandins are chemical messengers in the body that contribute to inflammation. Mesalazine is believed to inhibit the production of prostaglandins in the intestines, reducing inflammation and swelling.

Modulating Immune Response: Mesalazine may also modulate the immune response in the intestinal mucosa. It helps to regulate the activity of immune cells involved in the inflammatory process, thereby reducing the overall inflammatory response.

Scavenging Free Radicals: Mesalazine has antioxidant properties, which means it can neutralize harmful molecules called free radicals. Free radicals can contribute to tissue damage and inflammation, and mesalazine's antioxidant effects may help mitigate these effects.

Maintaining Mucosal Barrier: Mesalazine may contribute to the maintenance of the mucosal barrier in the intestines. This barrier is important for protecting the intestinal lining and preventing the penetration of harmful substances.

Dosage & Administration of Mesacol Suppository

• For rectal use only. Use this medicine as prescribed by your doctor.
• Wash and dry your hands after emptying your bowel.
• Insert the suppository in your rectum region through the anal opening after peeling off any wrapping over it.
• Do not move or walk for 15 minutes so that the medicine starts dissolving due to the body's temperature.
• Rewash your hands.
• Avoid passing stools for at least 1 hour so that medicine stays in place.

Interaction

May interact with non-steroidal anti-inflammatory drugs, immunosuppressants, anticoagulants, and laxatives.

Contraindications

Inform the doctor of any allergies, conditions, or medications.

Pregnancy & Lactation

Consult your doctor before use during pregnancy or breastfeeding.

Precautions & Warnings

• Inform your doctor about medical conditions, sensitivities, and current medications.
• Not recommended for pregnant or breastfeeding women unless necessary.
• Caution in severe kidney or liver failure, and blood abnormalities like porphyria.
• Avoid swallowing Mesacol Suppository 5's; consult a doctor if accidental ingestion occurs.

Storage Conditions

Store Mesacol Suppository 5's in a cool, dry place away from sunlight.