Prodep 20mg Capsule 10pcs

✔️ Prodep/Fluoxetine is indicated for the treatment of:

• Depressive illness
• Bulimia nervosa
• Obsessive-compulsive disorder (OCD)

Use this medication under the supervision of a registered healthcare provider.

✔️ How does Prodep/Fluoxetine work?

Fluoxetine works by increasing the levels of a chemical substance in the brain called serotonin. This helps in reducing the symptoms by maintaining normal brain function. Thus, it helps to improve your mood and a feeling of well-being.

✔️ Side Effects

• Gastrointestinal: Nausea, vomiting, dyspepsia, dry mouth, diarrhea.
• Neurological: Anxiety, nervousness, insomnia, drowsiness, fatigue.
• Other: Excessive sweating, pruritus, and skin rashes associated with liver, kidney, and lung involvement. Discontinue therapy if a rash develops.

✔️ Dosage & Administration

• Initial Treatment: The recommended starting dose is 20 mg/day, taken in the morning. This dose may be increased after several weeks if there is no clinical improvement, but should not exceed 80 mg/day. Dosages above 20 mg/day should be split into two doses (morning and noon).
• Maintenance Treatment: For ongoing management of depressive illness, Fluoxetine may be taken at 60 mg/day. It is also commonly used at 60 mg/day for bulimia nervosa.
• Use in Children: The use of Fluoxetine in children is not recommended, as safety and efficacy have not been established.
• Renal & Hepatic Impairment: Lower or less frequent dosages may be necessary for patients with kidney or liver issues.

✔️ Interaction

• MAO Inhibitors: Serious, sometimes fatal reactions may occur if used with MAOIs. Fluoxetine should not be combined with MAOIs or used within 14 days of stopping an MAOI. A 5-week wait is advised after discontinuing Fluoxetine before starting an MAOI.
• Antidepressants: Concurrent use with other antidepressants may increase their plasma levels.
• Lithium: Fluoxetine may increase or decrease lithium levels.
• Antipsychotics: May elevate blood levels of haloperidol and clozapine.
• Anticonvulsants: Can increase plasma levels of phenytoin and carbamazepine, leading to potential toxicity.
• CNS Active Drugs: Caution is advised with other centrally acting medications.

✔️ Contraindications

• Known hypersensitivity to Fluoxetine.
• MAO Inhibitors: Should not be used in combination with MAOIs or within 14 days of stopping MAOI therapy.

✔️ Pregnancy & Lactation

• Animal studies show no teratogenic effects, but since animal studies are not always predictive of human responses, Fluoxetine should only be used during pregnancy if necessary.
• Fluoxetine is excreted in breast milk, so it should be used cautiously in nursing women.

✔️ Precautions & Warnings

• Use with caution in patients with liver or kidney impairment and in those with a history of epilepsy.
• Fluoxetine can alter glycemic control, so diabetic patients should use it cautiously.
• Patients with suicidal tendencies should be carefully monitored during treatment.
• Not typically recommended for treating the depressive phase of bipolar disorder as it may trigger mania.

✔️ Storage Conditions

• Protect from light and moisture.
• Store in a cool, dry place, below 30°C.
• Keep out of reach of children.