Polycef 1gm/vial belongs to the first generation of cephalosporins. It works by interfering with the synthesis of the bacterial cell wall, causing the bacteria to rupture and die.
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Common side effects include gastrointestinal disturbances and hypersensitivity reactions like rashes and urticaria. Rare side effects include dizziness, nausea, vomiting, and abdominal pain.
Symptoms of overdose are nausea, vomiting, and diarrhea. Treatment is supportive, and gastric lavage may be necessary if a large amount has been ingested.
Concurrent use of nephrotoxic drugs like aminoglycosides may increase the risk of kidney damage. Diuretics and probenecid may also enhance renal toxicity.
Polycef should not be used in patients with known hypersensitivity to cephalosporins.
Polycef is categorized as US FDA Pregnancy Category B. It should be used during pregnancy only if clearly needed. It is excreted in human milk, so caution is advised when administered to breastfeeding women.
Prolonged use may lead to superinfection due to resistant organisms. Patients with penicillin allergies should use it with caution. Dosage adjustments are necessary for patients with renal impairment.
Reconstituted injection solutions should be used within 2 hours at room temperature or within 12 hours if refrigerated.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.