Fixbac DS (Cefixime) | A broad-spectrum oral cephalosporin antibiotic
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Fixbac DS is used to treat a variety of bacterial infections including:
Common: Nausea, vomiting, abdominal pain, diarrhea, and indigestion
Serious (rare): Pseudomembranous colitis, hypersensitivity reactions, rash, eosinophilia, thrombocytopenia
Cefixime disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), halting peptidoglycan formation and leading to cell death.
Probenecid: May raise cefixime blood levels
Oral anticoagulants: May increase bleeding risk via prolonged prothrombin time
Adults: 200–400 mg daily as a single or divided dose
Children >6 months: 8 mg/kg/day in 1–2 divided doses
Typhoid fever: 15–20 mg/kg/day in 2 divided doses (max 400 mg/day)
Gonorrhea: Single 400 mg dose
Renal impairment: Max 200 mg/day if CrCl <20 mL/min
May be taken with or without food. Maintain regular dosing intervals.
Considered safe during pregnancy based on decades of observational data. Caution in breastfeeding; no confirmed risk, but excretion in human milk is possible.
Store below 30°C, protected from moisture and light. Keep out of reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.