Cefim-3 DS contains Cefixime, an orally active, third-generation cephalosporin antibiotic with broad-spectrum bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It is highly stable against β-lactamase enzymes, making it effective against pathogens resistant to many penicillins and some cephalosporins.
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Cefim-3 DS is indicated for the treatment of the following acute infections caused by susceptible microorganisms:
Common pathogens include Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Klebsiella spp., Haemophilus influenzae (β-lactamase positive and negative), Moraxella catarrhalis (β-lactamase positive and negative), and Enterobacter spp.
Use with caution in patients with penicillin allergy (possible cross-reactivity).
Discontinue immediately if hypersensitivity reactions (rash, urticaria, anaphylaxis) occur.
Use cautiously in renal impairment (dose adjustment required).
Prolonged use may cause superinfection, including Clostridium difficile-associated diarrhea.
Should not be used in pregnancy or breastfeeding unless essential and prescribed by a physician.
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অ্যাপ থেকে অর্ডারের সহজ ভিডিও গাইড
অ্যাপ ডাউনলোডDownload ePharma App বিস্তারিত গাইড ›Detailed App Ordering GuideGenerally well tolerated. Most reactions are mild and self-limiting.
Common:
Diarrhea, loose stools, abdominal pain, nausea, dyspepsia, flatulence, vomiting.
Less common:
Headache, dizziness.
Hypersensitivity: rash, pruritus, urticaria, arthralgia, drug fever.
Hematological: thrombocytopenia, leukopenia, eosinophilia.
Mild transient changes in liver or renal function tests.
Serious (rare):
Pseudomembranous colitis (potentially life-threatening).
Treatment usually lasts 7 days, extendable to 14 days if clinically required.
200–400 mg daily (as a single dose or divided into two doses).
Gonorrhea: 400 mg single dose.
Typhoid fever: 20 mg/kg/day in 2 divided doses for 10–14 days.
Recommended dose: 8 mg/kg/day (single or divided doses).
General guide (suspension):
6 months–1 year: 3.75 ml daily
1–4 years: 5 ml daily
5–10 years: 10 ml daily
Safety and efficacy not been established.
Same as adult dose, unless severe renal impairment is present.
CrCl ≥20 ml/min: standard dosing.
CrCl <20 ml/min or dialysis patients: maximum 200 mg once daily.
May prolong prothrombin time; caution with anticoagulants (e.g., warfarin).
Hypersensitivity to cephalosporins or any component of the formulation.
Pregnancy: Limited data; use only if clearly needed.
Lactation: Unknown if excreted in human milk; caution advised.
Store below 30°C, protected from light and moisture.
Keep out of reach of children.
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