Cabolin 0.5mg Tablet (4pcs box)

✔️ Dosage & Administration:

For Hyperprolactinemia

The usual starting dose is 0.25 mg twice weekly. Depending on the patient's serum prolactin level and response to treatment, the dose may be increased by 0.25 mg twice weekly.

Dose increases should generally be made no more frequently than every 4 weeks to allow adequate assessment of response and tolerability. The dose should be individualized according to the lowest dose that provides an adequate response.

In patients who maintain normal prolactin levels for an extended period, the physician may consider discontinuing treatment with periodic monitoring to determine whether treatment needs to be restarted.

To Prevent Lactation

A single 1 mg dose is generally taken on the first day after delivery when suppression of lactation is indicated.

To Suppress Established Lactation

A total dose of 0.5 mg, divided into two doses of 0.25 mg taken 12 hours apart for one day, may be used when medically appropriate.

For Other Conditions Associated with Elevated Prolactin

Treatment is generally initiated with a low dose, such as 0.5 mg per week, divided into one or two doses. The dose may be gradually adjusted according to serum prolactin levels and clinical response.

The maximum dose may be increased under specialist supervision when necessary.

Do not change the dose or frequency without medical advice.

✔️ An overdose may cause symptoms such as:

• Nausea or vomiting
• Nasal congestion
• Dizziness or fainting
• Low blood pressure
• Hallucinations or other psychiatric symptoms

Supportive treatment and monitoring of blood pressure may be required. Seek immediate medical attention if an overdose is suspected.

✔️ Cabolin may interact with certain medicines, including:

• Medicines that lower blood pressure: May increase the risk of low blood pressure, particularly when standing.
• Antipsychotic medicines: Examples include chlorpromazine and haloperidol. These medicines may reduce or interfere with the effects of cabergoline.
• Medicines for nausea and vomiting: Certain dopamine-blocking medicines, such as metoclopramide and domperidone, may reduce the effectiveness of cabergoline.
• Other ergot-derived or dopamine agonist medicines: Examples include bromocriptine, pergolide, lisuride, ergotamine, dihydroergotamine, ergometrine, and methysergide.

✔️ Side Effects

• Nausea or vomiting
• Headache
• Dizziness
• Abdominal discomfort
• Constipation
• Fatigue
• Low blood pressure, particularly on standing
• Nasal congestion
• Drowsiness

✔️ Pregnancy & Lactation

Women who are pregnant, planning pregnancy, or who may become pregnant should discuss cabergoline treatment with their doctor.

Pregnancy should generally be excluded before treatment is initiated when cabergoline is being used for hyperprolactinemia. If pregnancy occurs during treatment, the physician should be informed so that the need for continued treatment can be reassessed.

Cabergoline suppresses prolactin secretion and therefore reduces or prevents breast milk production. It should not be used by women who intend to establish or continue breastfeeding unless specifically prescribed for another medical reason.

✔️ Cabolin should not be used in patients with:

• Hypersensitivity to cabergoline, other ergot-derived medicines, or any component of the formulation.
• A history of serious psychiatric disorders, particularly psychotic disorders, where cabergoline is considered unsuitable.
• Severe liver disease.
• Pregnancy-associated hypertension or conditions such as pre-eclampsia or eclampsia, unless specifically considered appropriate by the treating physician.
• A history of fibrotic disorders associated with previous long-term dopamine agonist treatment, particularly involving the heart, lungs, or abdomen.

✔️ Use Cabolin cautiously in patients with:

• Liver impairment
• A history of low blood pressure or blood-pressure-related problems
• Cardiovascular disease
• A history of serious psychiatric disorders
• Conditions associated with pulmonary, pleural, or retroperitoneal fibrosis
• Previous heart-valve disorders

✔️ Storage:

Store in a cool, dry place protected from light. Keep the medicine out of reach of children.