Trumega | Omega-3 Acid Ethyl Esters | 100mg | 30pcs Pot | Price | ePharma
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Trumega 1000mg Capsule (30pcs Pot)

Generic: Omega 3

Type: Capsule

Pack Size: 30 Pcs

Omega-3-acid ethyl esters are used with a proper diet to lower very high triglyceride (fat-like substance) levels in the blood. This medicine may help prevent medical problems caused by clogged blood vessels such as heart attacks and strokes.


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Discount Price: ৳ 564
MRP: ৳ 600 6% Off

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✅ Description:

Dyslipidemia

Dyslipidemia refers to abnormal levels of lipids (cholesterol, triglycerides, or both) in the blood. This condition can include high levels of low-density lipoprotein (LDL) cholesterol (bad cholesterol), low levels of high-density lipoprotein (HDL) cholesterol (good cholesterol), or high levels of triglycerides.

Causes:

  • Genetic factors (familial hypercholesterolemia)
  • Poor diet (high in saturated fats and cholesterol)
  • Lack of physical activity
  • Obesity
  • Smoking
  • Excessive alcohol intake
  • Certain medical conditions (diabetes, hypothyroidism, kidney disease)
  • Medications (some diuretics, beta-blockers, and corticosteroids)

Symptoms:

  • Often asymptomatic until it leads to cardiovascular diseases (heart attack, stroke)
  • Xanthomas (fatty deposits under the skin)
  • Corneal arcus (white or gray ring around the cornea)

Diagnosis:

  • Blood tests measure total cholesterol, LDL, HDL, and triglyceride levels.

Treatment:

  • Lifestyle changes (diet, exercise, weight loss, smoking cessation)
  • Medications (statins, fibrates, niacin, omega-3 fatty acids)

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✔️ Hypertriglyceridemia

Hypertriglyceridemia is a condition characterized by elevated levels of triglycerides (a type of fat) in the blood. High triglyceride levels can increase the risk of cardiovascular diseases and pancreatitis.

Causes:

  • Genetic predisposition (familial hypertriglyceridemia)
  • Poor diet (high in sugars and fats)
  • Obesity
  • Lack of physical activity
  • Excessive alcohol intake
  • Certain medical conditions (diabetes, hypothyroidism, kidney disease)
  • Medications (oral contraceptives, beta-blockers, steroids)

Symptoms:

  • Often asymptomatic
  • When extremely high, can cause pancreatitis (severe abdominal pain, nausea, vomiting)
  • Xanthomas
  • Hepatosplenomegaly (enlarged liver and spleen)

Diagnosis:

  • Blood tests measure triglyceride levels.

Treatment:

  • Lifestyle modifications (diet, exercise, weight loss, alcohol reduction)
  • Medications (fibrates, omega-3 fatty acids, statins)
✔️ Prophylaxis of Myocardial Infarction

Prophylaxis of myocardial infarction (heart attack) refers to the measures taken to prevent the occurrence of a heart attack, particularly in individuals at high risk or those who have already had a myocardial infarction.

Primary Prophylaxis:

  • Focuses on preventing the first occurrence of a heart attack.

Secondary Prophylaxis:

  • Aims to prevent recurrent heart attacks in patients who have already experienced one.

Lifestyle Modifications:

  • A healthy diet (low in saturated fats, high in fruits, vegetables, and whole grains)
  • Regular physical activity
  • Smoking cessation
  • Weight management
  • Limiting alcohol intake

Medications:

  • Antiplatelet agents (aspirin, clopidogrel)
  • Statins (to lower cholesterol levels)
  • Beta-blockers (to reduce blood pressure and heart workload)
  • ACE inhibitors or ARBs (to control blood pressure and protect the heart)
  • Omega-3 fatty acids (to lower triglycerides and provide cardiovascular benefits)

Monitoring and Management of Risk Factors:

  • Regular check-ups to monitor blood pressure, cholesterol levels, and diabetes control
  • Stress management and mental health support

In high-risk patients, procedures like angioplasty or coronary artery bypass surgery may be considered.

✔️ Uses of Trumega 1000mg Capsule
  1. Dyslipidemia
  2. Hypertriglyceridemia
  3. Prophylaxis of Myocardial Infarction
✔️ How does Trumega 1000mg Capsule work?

The active ingredients, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain n-3 polyunsaturated fatty acids.

  • Hypolipidemic Effect: Reduce plasma triglycerides by decreasing very low-density lipoproteins (VLDL).
  • Anti-inflammatory Action: Affect leukotriene synthesis, reducing inflammation.
  • Antiplatelet Effect: Influence prostanoid synthesis, leading to vasodilation, reduced platelet aggregation, increased bleeding time, and decreased platelet counts.
✔️ Dosage:

Adult Dose:

  • Hypertriglyceridemia: 4 g once daily or 2 g twice daily.
  • Secondary Prophylaxis of Myocardial Infarction: 1 g daily with food.
  • Joint Inflammation (Mild Arthritis): 2.7 g daily.
  • Mood Disorders & Impulse Control, Age-Related Macular Degeneration: 1 g daily.
  • Patients should follow a lipid-lowering diet during treatment.

Children (<18 years):

  • Safety and efficacy not established.
✔️ Side Effects:
  • Immune System Disorders: Rare - hypersensitivity.
  • Metabolism/Nutrition Disorders: Uncommon - hyperglycemia, gout.
  • Nervous System Disorders: Uncommon - dizziness, dysgeusia, headache.
  • Vascular Disorders: Uncommon - hypotension.
  • Respiratory Disorders: Uncommon - epistaxis.
  • Gastrointestinal Disorders: Common - abdominal distension, pain, constipation, diarrhea, dyspepsia, flatulence, eructation, gastroesophageal reflux, nausea/vomiting; Uncommon - gastrointestinal hemorrhage.
  • Hepatobiliary Disorders: Rare - liver disorders (transaminase increase).
  • Skin Disorders: Uncommon - rash; Rare - urticaria.
✔️ Composition:
  • Each soft gelatin capsule contains 1000 mg of Omega-3-Acid Ethyl Esters BP, which includes:
    • Eicosapentaenoic Acid BP: 80 mg
    • Docosahexaenoic Acid BP: 120 mg
✔️ Administration:

Should be taken with food to enhance absorption.

✔️ Trumega: Omega-3-Acid Ethyl Esters
  1. Adjunct to diet for reducing very high triglyceride levels (>500mg/dl) in adult patients.
  2. Secondary prevention in patients who have had a myocardial infarction within the past 3 months.
  3. Reduction of joint inflammation associated with mild arthritis.
  4. Management of mood disorders and impulse control.
  5. Prevention of age-related macular degeneration.
✔️ Pharmacology:
  • Omega-3-acid ethyl esters reduce triglyceride production in the liver. They inhibit acyl-CoA:1,2-diacylglycerol acyltransferase, reducing triglyceride synthesis and increasing beta-oxidation, which increases fatty acid metabolism. They also inhibit the release of fatty acids, increase triglyceride clearance by enhancing lipoprotein lipase activity, and decrease VLDL-C production.
✔️ Interactions:
  • No hemorrhagic complications have been noted with warfarin, but prothrombin time must be monitored when used together.
✔️ Contraindications

Hypersensitivity to any component of the medication.

✔️ Precautions:
  • Hemorrhagic Disorders: Use with caution in patients with bleeding disorders or those on anticoagulants or antithrombotic drugs.
  • Asthma: Asthmatic patients sensitive to aspirin should be used with caution.
  • Hepatic Impairment: Monitor hepatic function, especially in patients receiving high doses.
  • Lactation: It is not known if this medication is excreted in breast milk; use with caution.
✔️ Pregnancy & Lactation:
  • Should be used during pregnancy only if the benefit justifies the risk to the fetus. Unknown if excreted in human milk; use with caution in lactating mothers.
✔️ Precautions & Warnings:
  • Monitor bleeding time in patients on anticoagulant therapy and adjust dosage if necessary.
  • Increased bleeding time in high-risk patients (e.g., trauma, surgery).
  • Not recommended for children due to lack of data.
  • Monitor ASAT and ALAT levels in patients with liver damage signs, especially with high dosages.
  • Not indicated for exogenous hypertriglyceridemia (type 1 hyperchylomicronemia). Limited experience with secondary endogenous hypertriglyceridemia.
✔️ Storage Conditions:
  • Store below 25°C in a dry and cool place.
Frequently Asked Questions (FAQ)

(Omega-3-acid ethyl esters) is used to manage several conditions: Dyslipidemia: Abnormal levels of lipids in the blood. Hypertriglyceridemia: Elevated levels of triglycerides. Prophylaxis of myocardial infarction: Preventing heart attacks, particularly in those who have had a myocardial infarction in the past 3 months. It is also used to help reduce joint inflammation associated with mild arthritis, mood disorders, impulse control, and age-related macular degeneration.

Trumega 1000mg Capsule works by: Reducing triglycerides: Inhibiting triglyceride synthesis and increasing fatty acid metabolism. Anti-inflammatory effects: Affecting leukotriene synthesis. Antiplatelet effects: Promoting vasodilatation, reducing platelet aggregation, and increasing bleeding time.

Yes, Trumega 1000mg Capsule should not be used in patients who have: Known hypersensitivity to Trumega 1000mg Capsule or any of its components. It should be used cautiously in patients with bleeding disorders, asthma, and hepatic impairment.

Common side effects of Trumega 1000mg Capsule include: Gastrointestinal issues: Dyspepsia, nausea, diarrhea, and abdominal pain. Musculoskeletal symptoms: Back pain and joint discomfort. Other mild effects: Taste perversion, rash, and flu-like symptoms. Rare but serious effects: Increased liver enzymes, which should be monitored in patients with hepatic impairment.
Ratings & Reviews

Md Niloy
1
Verified Buyer
09 Mar, 2024
বক্স ওপেন ছিলো। গায়ের রেট ৪৫০ টাকা, ডিসকাউন্ট দিয়ে রাখা হয়েছে ৫৫৮ টাকার মতো। ইনটেক পলি খোল ছিলো মনে হচ্ছে আগে কেউ খুলেছিলো।

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