✔ 100% Authentic Product
- Elagolix is a GnRH receptor antagonist that inhibits endogenous GnRH signaling by competitively binding to GnRH receptors in the pituitary gland.
- This leads to a dose-dependent suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), resulting in reduced levels of ovarian hormones like estradiol and progesterone.
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Cashback offer (Optional):
🔹 Foreign manufacturer products are not applicable for Cashback offer
Cash on Delivery - All over Bangladesh
Urgent Delivery - 2 Hours Dhaka City
ফ্রি ডেলিভারি! - ১৪৯৯ টাকা+ অর্ডারে ঢাকা
শহরে ।- ফ্রি ডেলিভারি! - ২৯৯৯ টাকা+ অর্ডারে ঢাকার
বাহিরে ।
✅ Description:
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Oragon 150
- Endometriosis.
✔️ Mode of Action
- Elagolix is an oral GnRH receptor antagonist.
- It inhibits GnRH signaling in the pituitary gland, reducing LH and FSH levels.
- This leads to decreased estradiol and progesterone, alleviating pain symptoms associated with endometriosis.
✔️ Dosage & Administration of Oragon 150
Before starting treatment:
- Ensure pregnancy is excluded.
- Start treatment within 7 days from the onset of menses.
Dosing Regimens:
Elagolix 150 mg:
- 1 tablet once daily, for up to 24 months.
- For moderate hepatic impairment, limit use to 6 months.
Elagolix 200 mg:
- 1 tablet twice daily, up to 6 months (especially in cases with coexisting dyspareunia).
- Do not exceed 6 months as it may reduce bone mineral density (BMD).
Hepatic Impairment:
- Severe hepatic impairment: Elagolix 200 mg is not recommended.
Children & Adolescents (<18 years):
- Safety and efficacy not established.
✔️ Side Effects of Oragon 150
- Hot flashes, night sweats, headache, nausea, amenorrhea, arthralgia, mood changes, bone loss, Insomnia, anxiety, elevated liver enzymes.
✔️ Overdose Effects of Oragon 150
- In case of overdose:
- Monitor for adverse reactions and provide appropriate symptomatic treatment.
✔️ Administration Instructions
- Dosage Timing: Take at the same time daily, with or without food.
✔️ Interactions
With Medicines:
- May potentiate P-gp substrates (e.g., digoxin) and CYP2C19 substrates (e.g., omeprazole).
- May antagonize CYP3A substrates.
- Consider dose adjustment of oral midazolam and rosuvastatin.
- Reduced efficacy when used with CYP3A inducers or estrogen-containing contraceptives.
With Food:
- No known food interactions.
✔️ Contraindications
- Pregnancy: Risk of early pregnancy loss if exposed during pregnancy.
- Osteoporosis: Increases the risk of further bone loss.
- Severe hepatic impairment.
- Concomitant use with strong OATP1B1 inhibitors (e.g., cyclosporine, gemfibrozil).
✔️ Pregnancy & Lactation
Pregnancy:
- Contraindicated as it may increase the risk of early pregnancy loss.
- Discontinue immediately if pregnancy is confirmed during treatment.
Lactation:
- No data on the presence of Elagolix in human milk or its effects on breastfed infants.
✔️ Precautions & Warnings
Bone Loss:
- Long-term use can lead to irreversible bone density reduction. Assess BMD for women at risk.
Menstrual Irregularities:
- May reduce the ability to recognize pregnancy. Perform pregnancy tests if suspected.
Mood Changes:
- Monitor for suicidal ideation, depression, anxiety, or worsening mood disorders.
Liver Function:
- May cause dose-dependent elevation of liver enzymes. Monitor for signs of liver injury.
Contraception:
- Use non-hormonal contraception during treatment and for 1 week after discontinuation.
✔️ Therapeutic Class
- Gonadotropin-releasing hormone (GnRH) antagonist.
✔️ Storage Conditions
- Store in a cool, dry place below 25°C, protected from light and moisture.
- Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
