Dotfix 1 is indicated for:
✔️ Gout management – Helps prevent and treat flare-ups.
✔️ Hyperuricemia treatment – Reduces uric acid levels in the blood.
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Dotfix 1 is an effective selective urate reabsorption inhibitor designed to reduce uric acid levels and prevent gout attacks. However, patients must adhere to proper dosage adjustments and precautions to minimize risks and side effects. Regular monitoring, especially for kidney and liver function, is crucial for safe use. Always consult your doctor before making changes to your treatment regimen.
✔ Effectively lowers uric acid levels
✔ Selective inhibition for fewer side effects
✔ Monitored dosage adjustments for optimal safety
💙 For a healthier, gout-free life, consult your doctor before starting Dotfix 1
Should only be used if the benefits outweigh the risks. Consult your doctor.
The drug is excreted in breast milk. Consult your doctor before breastfeeding.
It is unknown whether Dotfix 1 affects driving ability. Do not drive if you experience dizziness, drowsiness, or difficulty concentrating.
Patients should undergo regular liver function tests, as serious liver damage has been observed with some other uricosuric drug
Dotinurad, the active ingredient in Dotfix 1, selectively inhibits URAT1, preventing the reabsorption of uric acid in the kidneys. This leads to increased uric acid excretion, thereby lowering serum uric acid levels. Unlike some other urate-lowering drugs, Dotfix 1 has minimal impact on other uric acid transporters like ABCG2, OAT1, and OAT3, making it highly selective and efficient.
💊 Adults:
💊 Children:
💊 Renal Impairment:
🔹 Common side effects (1%–5% occurrence):
🔹 Rare side effects (<1% occurrence):
Note: If severe side effects occur, consult your doctor immediately.
⚠️ Medications that may reduce the effectiveness of Dotfix 1:
1️⃣ Pyrazinamide (Anti-TB drug):
2️⃣ Salicylates (Aspirin & related drugs):
💡 Consult your doctor before using Dotfix 1 with these medicationsgs.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.