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Ciclorox 1% Shampoo is a medicated shampoo specifically designed for the treatment of scalp conditions such as:
- Seborrheic dermatitis
- Dandruff (pityriasis capitis)
- Scalp inflammation and swelling
It helps relieve itchiness, flaking, and irritation associated with fungal overgrowth and inflammatory responses on the scalp.
Pediatric use: Safety and effectiveness have not been established in children under 16 years of age due to a lack of sufficient clinical trial data.
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✅ Description:
Ciclopirox Olamine is a synthetic, broad-spectrum antifungal compound with both fungistatic and fungicidal properties. It effectively targets:
- Dermatophytes: e.g., Trichophyton rubrum, T. mentagrophytes, Epidermophyton floccosum, Microsporum canis
- Yeasts: e.g., Candida albicans, and
- Malassezia furfur, a fungus commonly linked to dandruff and seborrheic dermatitis.
- The antifungal mechanism primarily involves:
- Disruption of fungal cell metabolism by interfering with the uptake of essential substrates and metal ions, which are necessary for fungal growth and survival.
- In addition to antifungal activity, Ciclopirox exhibits:
- Antibacterial effects against a range of both Gram-positive and Gram-negative bacteria.
- Anti-inflammatory properties, demonstrated by its ability to:
- Inhibit the production of pro-inflammatory mediators like prostaglandins and leukotrienes.
- Block key enzymes such as 5-lipoxygenase and cyclooxygenase, involved in inflammation pathways.
This triple-action profile (antifungal, antibacterial, anti-inflammatory) makes it highly effective in treating scalp conditions with both microbial and inflammatory components.
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✔️ Dosage & Administration of Ciclorox 1% Shampoo
Adults and adolescents (≥16 years):
- Wet the hair thoroughly.
- Apply approximately 5 ml (1 teaspoon) of shampoo to the scalp.
- For longer hair, up to 10 ml (2 teaspoons) may be used.
Massage gently to form a lather and leave the shampoo on the scalp for 3 minutes (a timer may help ensure adequate contact time).
- Rinse thoroughly.
- Frequency of Use:
- Use twice weekly for 4 weeks.
- Maintain a minimum gap of 3 days between applications.
- Avoid contact with the eyes. If contact occurs, rinse thoroughly with water.
✔️ Side Effects of Ciclorox 1% Shampoo
Ciclopirox shampoo is generally well tolerated, with minimal adverse reactions noted in clinical studies.
If any irritation, itching, or unusual symptoms occur, discontinue use and consult a healthcare provider.
✔️ Contraindications
Do not use in patients who have shown hypersensitivity or allergic reactions to any component of the formulation.
✔️ Pregnancy & Lactation
Pregnancy Category B: Animal studies have not demonstrated any fetal risk, but adequate and well-controlled studies in pregnant women are lacking.
It is unknown whether Ciclopirox is excreted in breast milk, so caution is advised when used by nursing mothers.
✔️ Precautions & Warnings
- This shampoo is for external use on the scalp only.
- Do not apply in or around the eyes, mouth, or vaginal area.
- Rinse thoroughly if accidental exposure occurs.
✔️ Storage Guidelines
- Store below 30°C, away from direct light and moisture.
- Keep the bottle tightly closed when not in use.
- Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
