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- Ciclopirox Olamine is a synthetic broad-spectrum antifungal agent that inhibits the growth of dermatophytes, yeasts, and Malassezia furfur.
- Ciclopirox Olamine depletes fungal cells of essential substrates and ions, preventing their uptake from the environment, and leading to growth inhibition or cell death.
- It is also active against many gram-positive and gram-negative bacteria.
- Ciclopirox reduces inflammation by inhibiting the synthesis of prostaglandins and leukotrienes and forming 5-lipoxygenase and cyclooxygenase in human polymorphonuclear cells.
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✅ Description:
Candirox Cream is used for the topical treatment of various skin infections, including:
- Tinea pedis, Tinea cruris, and Tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis.
- Candidiasis (moniliasis) caused by Candida albicans.
- Tinea (pityriasis) versicolor caused by Malassezia furfur.
Additionally, it is effective against certain gram-negative and gram-positive bacteria. Its anti-inflammatory properties make it suitable for treating mild to moderate inflammatory fungal infections.
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✔️ Side Effects
Generally well-tolerated with minimal adverse effects reported in clinical trials.
✔️ Dosage and Administration
Massage the cream onto the affected and surrounding skin areas twice daily for four weeks.
Symptom relief, such as reduced itching, is typically observed within the first week. For Tinea versicolor, clinical and mycological clearing often occurs after two weeks of treatment.
If no clinical improvement is observed after four weeks, the diagnosis should be reconsidered.
The safety and efficacy in children under 10 years have not been established.
✔️ Contraindications
Contraindicated in individuals with known hypersensitivity to any components of Ciclopirox Olamine cream.
✔️ Pregnancy and Lactation
- Pregnancy: Category B. No well-controlled studies in pregnant women exist. Use only if needed.
- Lactation: It is unknown if the drug is excreted in human milk. Caution should be exercised when used by nursing women.
✔️ Storage Conditions
- Store below 25°C and protect from light.
- Keep out of reach of children.
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