Valex CR 200 | Sodium Valproate 133.2mg + Valproic Acid 58mg | ePharma
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Valex CR 200mg Tablet 10pcs

Generic: Sodium Valproate+Valproic Acid

Type: Tablet

Pack Size: 10 Pcs

Valex CR 200mg Tablet is used:

  • Manage or control mania caused by bipolar disorder
  • Manage complex partial seizures (adults and children 10 years of age and older) and simple and complex absence seizures, with or without other types of seizure
  • Prevent migraine headaches

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Discount Price: ৳ 57
MRP: ৳ 60 5% Off

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✅ Description:

Sodium Valproate+Valproic Acid is a medication utilized to manage seizures in patients with epilepsy. It can be used alone or in combination with other medications to treat various types of seizures, including complex partial and absence seizures. Additionally, it is effective in managing manic episodes associated with bipolar disorder and can be prescribed for migraine prophylaxis. Sodium Valproate works by increasing certain brain chemicals that help control seizures.

When taking Sodium Valproate orally, it is recommended to consume it with or before meals, avoiding carbonated beverages to prevent throat irritation. Dosage depends on factors like age, health status, weight, and the severity of the condition being treated. Abrupt discontinuation of Sodium Valproate is not advised, as it should be tapered gradually to avoid complications.

Common side effects of Sodium Valproate may include dizziness, hair loss, tremors, diarrhea, changes in weight, and blurred or double vision. It's essential to monitor for mood swings and signs of depression, including suicidal thoughts, especially in certain individuals. In cases of overdose, immediate medical assistance is necessary, as symptoms may include coma, irregular heart rate, and extreme drowsiness.

Dosage typically ranges from 1000mg to 2000mg daily for adults and lower doses for children, starting from 25mg to 30mg. Allergic reactions to Sodium Valproate are rare but may manifest as a rash or chest pain accompanied by shortness of breath, warranting immediate medical attention.

Safety Advices


Alcohol
UNSAFE

Avoid alcohol as it can increase the risk of side effects.


Pregnancy
CONSULT YOUR DOCTOR

Discuss with your doctor before use if you are pregnant, planning to become pregnant, or breastfeeding.


Breastfeeding
CONSULT YOUR DOCTOR

Small quantities of this medicine pass into the breast milk and can affect your baby if you are breastfeeding the baby. Thus, it is recommended to consult your doctor if you are consuming this medicine and breastfeeding your baby.


Driving
UNSAFE

Exercise caution when driving or operating machinery until you know how the medication affects you.


Kidney
CONSULT YOUR DOCTOR

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.


Liver
CONSULT YOUR DOCTOR

Valex CR 200mg Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this

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✔️ Uses of Valex CR 200mg Tablet

Active Ingredients:

  • Sodium Valproate
  • Valproic Acid

Used in the treatment of epilepsy.

✔️ How does Valex CR 200mg Tablet work?

Sodium Valproate + Valproic Acid is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid. They work together to control seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

✔️ Side Effects of Valex CR 200mg Tablet
  • Nausea Or Vomiting
  • Diarrhea
  • Shakiness In The Legs, Arms, Hands Or Feet
  • Blurred Vision
  • Dizziness
  • Weight Gain
  • Body Pain
  • Skin Rash
  • Sneezing
  • Dry Or Scaly Skin
  • Rash
  • Alopecia
  • Tremor
✔️ Quick Suggestions:
  • Always follow the dosage prescribed by your doctor.
  • Take the medication at the same times each day to maintain even levels in your bloodstream.
  • Can be taken with or without food, although taking it with food may help reduce gastrointestinal side effects.
  • Regular monitoring of liver function, blood counts, and medication levels is necessary.
  • Do not stop taking the medication suddenly without consulting your doctor to avoid increased seizure frequency.
✔️ Indications:
  • Epilepsy:
    • Treats various forms of epilepsy, a brain-related disorder that leads to abnormal brain activity, seizures, uncontrolled movements, and loss of consciousness.
  • Bipolar Disorder:
    • Manages manic episodes associated with bipolar disorder, which includes symptoms such as extreme mood swings, including emotional highs (mania) and lows (depression).
✔️ Pharmacology

Valex CR Tablet works by stabilizing electrical activity in the brain, thereby preventing abnormal and excessive nerve cell activity. This helps control seizures and stabilize mood.

✔️ Dosage & Administration of Valex CR 200mg Tablet

Adult Dosage

1. Complex Partial Seizures:

  • Initial Dose: 10-15 mg/kg/day.
  • Titration: Increase by 5-10 mg/kg/day at weekly intervals.
  • Maximum Dose: Up to 60 mg/kg/day.

2. Simple & Complex Absence Seizures:

  • Initial Dose: 15 mg/kg/day, divided every 6-12 hours.
  • Titration: Increase by 5-10 mg/kg/day at weekly intervals.
  • Maximum Dose: Up to 60 mg/kg/day.

3. Migraine Prophylaxis:

  • Initial Dose: 250 mg twice daily.
  • Adjustment: Adjust based on clinical response.
  • Maximum Dose: 1000 mg/day.

4. Bipolar Mania:

  • Initial Dose: 750 mg/day in divided doses.
  • Adjustment: Adjust dose as rapidly as possible to achieve a desired therapeutic effect.
  • Maximum Dose: 60 mg/kg/day.

Hepatic Impairment:

  • Dose Adjustment: Administer lower doses.
  • Contraindication: Contraindicated in severe hepatic impairment.

Pediatric Dosage

1. Complex Partial Seizures:

  • <10 years: Safety and efficacy not established.
  • >10 years:
    • Initial Dose: 10-15 mg/kg/day.
    • Titration: Increase by 5-10 mg/kg/day at weekly intervals.
    • Maximum Dose: Up to 60 mg/kg/day.

2. Simple & Complex Absence Seizures:

  • >10 years:
    • Initial Dose: 250 mg twice daily.
    • Adjustment: Adjust based on clinical response.
    • Maximum Dose: Up to 1000 mg/day.

Renal Dose Adjustment

  • Renal Impairment: No adjustment necessary.

Take the Valex CR Tablet exactly as directed by your doctor. This medication can be taken with or without food. Taking it with food may help reduce gastrointestinal side effects. It's important to take it at the same time each day to maintain even levels of the medication in your bloodstream.

✔️ Interaction

1. Drug-Drug Interactions:

  • Aspirin
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Carbamazepine
  • Lamotrigine
  • Felbamate
  • Zidovudine
  • Amitriptyline
  • Sertraline
  • Quetiapine
  • Olanzapine
  • Risperidone
  • Levonorgestrel
  • Mefloquine
  • Cimetidine
  • Imipenem
  • Meropenem
  • Erythromycin
  • Cholestyramine
  • Clonazepam
  • Diazepam

2. Drug-Food Interactions:

  • Avoid alcohol consumption as it may increase dizziness and sleepiness, and provoke seizures.

3. Drug-Disease Interactions:

  • Inform your doctor if you have depression, liver disease, urea cycle disorders, suicidal tendencies, HIV disease, or thrombocytopenia.
✔️ Contraindications

Sodium Valproate is contraindicated for patients who have known hypersensitivity to the drug and liver dysfunction. Use of Sodium Valproate is restricted during pregnancy and in women of childbearing potential

✔️ Pregnancy & Lactation

Pregnancy:

  • Placental Transfer: Sodium Valproate crosses the placenta, posing potential risks to the fetus.
  • Neural Tube Defects: Exposure during the first trimester may lead to neural tube defects like anencephaly and spina bifida in newborns.
  • Monitoring: Pregnant women on Sodium Valproate treatment should undergo serum alpha-fetoprotein estimation.
  • Risk Assessment: Discuss the risks and benefits with your healthcare provider before continuing or discontinuing treatment during pregnancy.

Lactation:

  • Excretion in Breast Milk: Sodium Valproate is excreted in breast milk.
  • Potential Risks: While breastfeeding by mothers on Sodium Valproate treatment likely poses no significant risk to the child, careful monitoring and consultation with a healthcare provider are advisable.
  • Risk-Benefit Evaluation: Considerations regarding breastfeeding should be made in consultation with your healthcare provider, weighing the benefits of breastfeeding against the potential risks associated with Sodium Valproate exposure.
✔️ Precautions & Warnings
  1. Allergy: Do not take if allergic to any of its components.
  2. Liver Problems: Avoid if you have/had liver issues.
  3. Porphyria: Avoid in case of this blood disorder.
  4. Bleeding Susceptibility: Not recommended if prone to bleeding.
  5. Inflammatory Diseases: Inform your doctor if you have inflammation-related conditions.
  6. Bone Marrow Damage: Consult your doctor if you have bone marrow damage.
  7. Kidney Problems: Inform your doctor if you have kidney issues.
  8. Adverse Effects: Report weakness, loss of appetite, lack of interest, seizure recurrence, prolonged bleeding, or abdominal pain.
  9. Suicidal Tendencies: Seek immediate medical attention if experiencing suicidal thoughts.
  10. Pregnancy: Avoid during pregnancy due to the risk of birth defects.
  11. Contraception: Use effective contraception if of child-bearing age.
  12. Breastfeeding: Consult your doctor before breastfeeding.
  13. Drowsiness/Dizziness: May cause drowsiness and dizziness; avoid driving or operating machinery.
  14. Alcohol: Avoid alcohol consumption as it may increase dizziness and the risk of seizures.
  15. Children Below 3 Years: Use caution due to a higher risk of liver intoxication during the initial treatment period.
✔️ Storage Conditions:

Store below 30°C. Keep away from light and moisture. Ensure that the medication is kept out of the reach of children.

Frequently Asked Questions (FAQ)

A: Valex CR Tablet is a combination medicine containing sodium valproate and valproic acid as active ingredients. It is used for treating all types of epilepsy and manic episodes associated with bipolar disorder.

A: No, Valex CR Tablet does not cause addiction. However, it should only be taken as prescribed by your doctor to avoid any potential adverse effects. Self-medication can lead to severe consequences.

A: It's best to avoid alcohol while taking Valex CR Tablet, as it may affect how the medicine works.

A: This medicine should be taken with or after food as prescribed by your doctor.
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Check our pricing section for Valex CR 200mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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