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Osmolax Oral Solution 100ml
Lactulose, the active ingredient, is a synthetic disaccharide that is metabolized in the colon by saccharolytic bacteria. This process produces organic acids, primarily lactic acid, which lowers the pH of the colon contents, promoting water retention via an osmotic effect and increasing peristalsis.
Lactulose is minimally absorbed, and its principal therapeutic action is in the colon.
Osmolax is a hyperosmolar laxative that works by drawing water into the bowel, causing distention through fluid accumulation, which softens the stool and accelerates bowel movement. It is a non-absorbable disaccharide that does not get absorbed into the bloodstream.
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✅ Description:
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✔️ Osmolax is indicated for the treatment of the following conditions:
- Chronic Constipation: Should be used when dietary fiber, fluids, and physical activity are insufficient.
- Intestinal Flora Disturbances: Especially after long-term antibiotic treatment.
- Gall Bladder Diseases.
- Intestinal Diseases: Including colitis, diverticulosis, and megacolon.
- Increased Blood Ammonia Levels: Such as in hepatopathy or portal-systemic encephalopathy.
✔️ Dosage & Administration
Chronic Constipation:
- Adults: 3-6 teaspoons daily initially, then 1½-6 teaspoons for long-term therapy.
- Children up to 14 years: 3 teaspoons initially, 1-2 teaspoons for long-term therapy.
- Infants and Toddlers: 1-2 teaspoons initially, then 1 teaspoon for long-term therapy.
Damaged Intestinal Flora:
- Adults: 1-2 teaspoons daily.
- Children: 1 teaspoon daily.
Reduction of Blood Ammonia Levels:
- Hyperammonemia in Hepatopathy: 18-30 teaspoons daily.
- Portal Systemic Encephalopathy: 6-9 teaspoons hourly until laxation is achieved, then reduce the dose.
Use as directed by a registered healthcare professional.
✔️ Side Effects
- Common: Flatulence, cramps, and abdominal discomfort, especially at the start of treatment. These can be reduced by adjusting the dose.
- Overdose: Can cause diarrhea. Long-term abuse may result in electrolyte imbalance, particularly potassium loss.
✔️ Interaction
No significant drug interactions have been reported. However, potassium deficiency from abuse may intensify the effects of cardiac glycosides.
✔️ Contraindications
- Hypersensitivity to galactose or lactose.
- Patients on a galactose-free diet.
- Gastro-cardinal symptom complex.
- Suspected intestinal obstruction.
✔️ Pregnancy & Lactation
Pregnancy: Lactulose has no known adverse effects (FDA Category B). The decision to use during pregnancy and lactation should be made by a registered physician.
✔️ Precautions & Warnings
- Caution should be used when administering Osmolax to patients with known intolerance.
- Higher doses required for hepatic coma treatment may affect diabetics.
✔️ Storage Conditions
- Store in a dry place, away from light and heat.
- Keep out of reach of children.
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