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Chronic Constipation:
For chronic constipation, initial management should focus on lifestyle modifications such as a high-fiber diet (including vegetables, fruits, and salads), adequate fluid intake, and regular physical activity. Lactu should be used only when these measures fail to provide sufficient relief.
Disturbances of Intestinal Flora:
Lactu may be beneficial in restoring normal intestinal flora, particularly following prolonged antibiotic therapy.
Other Indications:
- Gallbladder disorders
- Intestinal diseases (e.g., colitis, diverticulosis, megacolon)
Elevated blood ammonia levels are associated with hepatopathy or portal-systemic encephalopathy
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Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery - 12-24 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery - 24-48 Hours, Other Cities* Charge Tk.99-110
- ফ্রি ডেলিভারিঃ - ৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
✅ Description:
Lactu is a hyperosmolar laxative used effectively for the management of constipation. It contains lactulose, a non-absorbable disaccharide that draws water into the bowel lumen, leading to stool softening and stimulation of bowel movements through increased intestinal distention.
Lactulose is a synthetic disaccharide that undergoes metabolism in the colon by saccharolytic bacteria, producing low-molecular-weight organic acids (mainly lactic acid). These acids reduce colonic pH and retain water via osmotic action, thereby enhancing peristaltic activity and promoting defecation.
Since lactulose is minimally absorbed, its systemic pharmacokinetics are not relevant to its therapeutic effect.
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✔️ Dosage & Administration
For Chronic Constipation:
- Adults: Initially 3–6 teaspoons daily; for maintenance, 1½–6 teaspoons daily.
- Children (up to 14 years): Initially 3 teaspoons daily; maintenance dose 1–2 teaspoons daily.
- Infants & Toddlers: Initially 1–2 teaspoons daily; maintenance dose 1 teaspoon daily.
For Intestinal Flora Disturbances:
- Adults: 1–2 teaspoons daily.
- Children: 1 teaspoon daily.
For Hyperammonemia:
- In Hepatopathy: Up to 18–30 teaspoons daily.
In Portal-Systemic Encephalopathy: 6–9 teaspoons hourly until rapid laxation occurs, then reduce the dose as needed to maintain the desired effect.
✔️ Side Effects
Mild flatulence, abdominal cramps, or discomfort may occur at the start of therapy, usually resolving with dose adjustment. Overdosage may cause diarrhea and electrolyte imbalance (mainly potassium loss) if misused.
✔️ Interactions
No clinically significant drug interactions have been reported. However, excessive use may cause potassium depletion, potentially enhancing the effects of cardiac glycosides.
✔️ Contraindications
Hypersensitivity to lactulose, galactose, or lactose
Galactose-free diet
Gastro-cardiac symptom complex
Suspected intestinal obstruction
✔️ Pregnancy & Lactation
Lactulose is classified as FDA Pregnancy Category B, indicating no evidence of fetal risk in animal studies. It is considered safe for use during pregnancy and breastfeeding under medical supervision.
✔️ Precautions & Warnings
Use cautiously in patients with lactose intolerance.
High doses used for hepatic encephalopathy should be administered carefully in diabetic patients, as the solution may contain small amounts of absorbable sugars.
✔️ Storage Conditions
Store in a cool, dry place, protected from light and heat.
Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
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