Arimidex 1 Tablet 14pcs

✔️ Uses of Arimidex 1

Treatment of Breast cancer

✔️ How does Arimidex 1 work?

Arimidex contains anastrozole, a non-steroidal aromatase inhibitor.

• It reduces estrogen production by inhibiting the aromatase enzyme, which converts androgens to estrogen.
• This suppression helps slow or stop the growth of estrogen-dependent breast cancer cells.

✔️ Side Effects of Arimidex 1

• >10% incidence:
  • Hot flashes, joint pain (arthralgia), arthritis, osteoporosis, bone fractures, back pain.
  • Fatigue, weakness (asthenia), nausea, rash, headache, hypertension.
  • Depression, insomnia, peripheral edema, lymphedema.
• Serious but rare:
  • Severe skin reactions (ulcers, blisters).
  • Allergic swelling of the face, lips, or throat (angioedema).
  • Liver dysfunction with jaundice or pain.

✔️ Quick Suggestions:

• Arimidex 1mg Tablet is used for the treatment of hormone-dependent breast cancer in postmenopausal women.
• Take it at the same time every day.
• It may cause weakness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
• Nausea may occur on starting treatment with this medicine but should go away with time. If nausea is bothersome, take it after a meal.
• Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements if needed.
• Do not take Arimidex 1mg Tablet if you are pregnant or breastfeeding
• Your doctor may advise you to regularly measure body density before, during, and after the treatment as the Arimidex 1 Tablet may cause bone thinning due to the reduction of estrogen in the body.
• Arimidex 1 Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while you are taking it.

✔️ Indication of Arimidex 1

Arimidex 1 relieves the symptoms of breast cancer such as breast lumps, bloody discharge from the nipple, or changes in the shape or texture of the breast.

✔️ Breast Cancer

What is Breast Cancer?

Breast cancer occurs when cells in the breast grow uncontrollably. It is often linked to the female hormone estrogen, which can stimulate the growth of cancer cells. Breast cancer can originate in various parts of the breast:

1. Lobules: The milk-producing glands.
2. Ducts: Pathways that carry milk from lobules to the nipple.
3. Fatty and connective tissues: Other supportive structures within the breast.

Cancer cells can spread to nearby lymph nodes, providing a route for the disease to travel to other body parts.

Symptoms of Breast Cancer

Be alert to the following signs and symptoms, and consult a healthcare provider if they occur:

• Lump in the breast: A noticeable lump or tissue thickening that feels different from the surrounding tissue.
• Changes in breast size, shape, or appearance: Unexplained changes may indicate an abnormality.
• Breast pain: Persistent or unusual discomfort.
• Redness or swelling: Inflammation or abnormal changes in the breast skin.
• Nipple discharge: Discharge other than breast milk, especially bloody discharge.
• Peeling or flaking skin: Skin changes around the nipple or breast.
• Lump or swelling under the arm: This may indicate lymph node involvement.

How does Breast Cancer Spread?

The cancer cells can:

1. Invade nearby breast tissues and other healthy cells.
2. Travel to lymph nodes, which are critical in draining and filtering the lymphatic fluid.
3. Metastasize (spread) to other organs, including bones, liver, lungs, and brain.

Early Detection and Management

Regular screenings like mammograms and self-examinations can help detect breast cancer early when it is most treatable. Recognizing the symptoms and seeking prompt medical attention are crucial for improving outcomes.

Treatment options may include:

• Surgery (lumpectomy or mastectomy).
• Radiation therapy.
• Chemotherapy.
• Hormone therapy (e.g., aromatase inhibitors like Arimidex).
• Targeted therapy.

✔️ Dosage & Administration of Arimidex 1

• Standard Dose: One 1 mg tablet once daily.
• Duration:
  • Continue in advanced breast cancer until tumor progression.
  • For adjuvant therapy in early breast cancer, the optimal duration is unknown.
• No dose adjustment is necessary for mild-to-moderate hepatic or renal impairment.
• Pediatric Use: Safety and efficacy are not established.
• Geriatric Use: No significant differences in effectiveness or safety compared to younger patients.

Swallow it as a whole with water; do not crush, break, or chew it.

✔️ Interaction

Arimidex 1 Tablet may interact with disease conditions, including high cholesterol, osteoporosis (thinning of bone), heart disease, and liver disease. Using thalidomide (immunomodulatory agent) with Arimidex 1 Tablet can increase the risk of dangerous blood clots.

✔️ Contraindications:

• Pregnancy (Category X): Can cause fetal harm.
• Premenopausal women: Offers no clinical benefit.
• Hypersensitivity: Not suitable for patients allergic to anastrozole or its excipients.

✔️ Pregnancy & Lactation

• Pregnancy: Contraindicated due to potential fetal harm.
• Lactation: It is unknown if Arimidex passes into breast milk. Nursing is not recommended.

✔️ Precautions & Warnings

• Bone health: Arimidex can decrease bone mineral density, increasing the risk of osteoporosis. Consider supplements like calcium and vitamin D if advised.
• Cholesterol levels: Monitor serum cholesterol, as Arimidex may cause elevations.
• Cardiovascular health: Women with pre-existing ischemic heart disease are at higher risk of ischemic events.
• Drug interactions:
  • Avoid using tamoxifen or estrogen-containing therapies with Arimidex, as they reduce its effectiveness.

✔️ Storage:

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.