D-Vine 2000IU Oral Solution 50ml

Vitamin D3 deficiency can occur in people whose exposure to sunlight is limited and in those whose diet is deficient in vitamin D3.
 

• D-Vine is essential for the effective calcium and phosphate absorption required for healthy bones and teeth, preventing rickets, osteomalacia and osteoporosis.
• D-Vine is also essential to prevent pre-eclampsia during pregnancy and breastfeeding, as it is an essential nutrient for a growing infant.
• D-Vine has a vital role in boosting immunity.

For Oral Solution: 

• Up to one year: 400 IU once a day or as directed by the physician.
• 1 year to 18 years: 600 IU once a day or as directed by the physician.

Injection: For treatment-
 

• Rickets: 1 ampoule every 2 weeks for one month then 1 ampoule for every 4 months
• Osteoporosis: 1 ampoule every 2 weeks for 3 months
• Osteomalacia: 1 ampoule every 2 weeks for 3 months
• Tetany caused by hypocalcaemia: 1 ampoule for every 4 months which may be increased to 2 ampoules
• Menopause: 1 ampoule for every 6 months
• Vitamin 03 deficiency: 1 ampoule can be repeated 1 to 6 months later

Drug interaction with medication: Concomitant treatment with phenytoin or barbiturates can decrease the effect of vitamin D because of metabolic activation. Concomitant use of glucocorticoids can decrease the effect of vitamin D. The effects of digitalis and other cardiac glycosides may be accentuated with the oral administration of calcium combined with vitamin D. Strict medical supervision is needed and, if necessary, monitoring of ECG and calcium. Simultaneous treatment with ion exchange resins such as cholestyramine or laxatives such as paraffin oil may reduce the gastrointestinal absorption of vitamin D. The cytotoxic agent actinomycin and imidazole antifungal agents interfere with vitamin D activity by inhibiting the conversion of 25-hydroxyvitamin D to 1, 25-dihydroxyvitamin D by the kidney enzyme, 25-hydroxyvitamin D-1-hydroxylase.

Vitamin D3 is contraindicated in all diseases associated with hypercalcaemia. It is also contraindicated in patients with known hypersensitivity to Vitamin D3 (or medicines of the same class) and any of the excipients. It is contraindicated if there is evidence of Vitamin D3 toxicity.

Generally, all nutritional supplements are considered to be safe and well tolerated. However, a few of the most common side effects can generally occur, including hypocalcaemia syndrome or calcium intoxication (depending on the severity and duration of hypocalcaemia); occasional acute symptoms include anorexia, headache, nausea, vomiting, abdominal pain or stomach ache, and constipation with the administration of colecalciferol.

Studies have shown safe use of doses up to 4000 IU during pregnancy. The recommended daily intake for pregnant women is 400 IU; however, in women who are considered to be Vitamin D3 deficient, a higher dose may be required. During pregnancy, women should follow the advice of their medical practitioner as their requirements may vary depending on the severity of their disease and their response to treatment

Vitamin D3 and its metabolites are excreted in breast milk. Overdose in infants induced by nursing mothers has not been observed; however, when prescribing additional vitamin D3 to a breast-fed child, the practitioner should consider the dose of any additional vitamin D3 given to the mother.

Plasma-calcium concentration should be monitored at intervals in patients receiving high doses of Vitamin D3, in renal impairment, and during pregnancy & lactation. People using Digoxin and Thiazide Diuretics should consult a health care practitioner before supplementing with Vitamin D3. People with liver or kidney disease, primary hyperthyroidism, lymphoma, tuberculosis and granulomatous disease should consult a health care practitioner before supplementing with Vitamin D3.

Store in a cool (below 25°C) and dry place protected from light. Keep out of reach of children.