Vitamin D3 (Cholecalciferol) is converted in the liver to 25-hydroxy Vitamin D3 (Calcidiol) and subsequently in the kidneys to the active metabolite, Calcitriol.
Calcitriol acts by binding to Vitamin D receptors (VDRs) throughout the body, increasing intestinal calcium and phosphate absorption necessary for:
Being fat-soluble, Vitamin D3 is stored in adipose tissue and muscle, with a long biological half-life of approximately 50 days.
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D-20000 is indicated for:
Vitamin D deficiency is more common in individuals with limited sunlight exposure or inadequate dietary intake.
These medicines may reduce Vitamin D absorption or increase calcium-related complications.
Careful monitoring is advised in patients with:
Serum calcium levels should be monitored during high-dose therapy.
Store below 25°C in a cool, dry place away from light and moisture. Keep out of reach of children.
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