Xyflo 10mg Tablet

Uses of Xyflo 10

• Asthma Prevention
• Sneezing and Runny nose due to allergies

How to use Xyflo 10

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xyflo 10 may be taken with or without food, but it is better to take it at a fixed time.

How Xyflo 10 works

Xyflo 10 works by blocking the action of leukotriene, a chemical messenger. This reduces inflammation in the airways to prevent asthma and relieve symptoms of allergies.

What if you forget to take Xyflo 10?

If you miss a dose of Xyflo 10, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects of Xyflo 10

• Nausea
• Vomiting
• Headache
• Diarrhea

Quick Suggestions:

• You have been prescribed Xyflo 10 for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose.
• It is a relatively safe medicine with very few side effects.
• Take Xyflo 10 2 hours before exercising if you have exercise-induced asthma.
• It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
• Do not discontinue use without consulting your doctor, even if you feel better.

Indications of Xyflo 10

Xyflo 10 Tablet is an anti-allergic medication that contains Montelukast. Montelukast is a leukotriene antagonist, which blocks a chemical messenger (leukotriene) and reduces inflammation and swelling in the nose and lungs, making it easy to breathe and helping them to improve symptoms and treat a broad range of allergic conditions, thereby minimizing symptoms like sneezing, runny nose, coughing, watery eyes, etc.

Pharmacology

XyfloTM is a medication that belongs to a class of drugs known as leukotriene receptor antagonists. It specifically targets and blocks the activity of the cysteinyl leukotriene receptor (CysLT1). This receptor is involved in the response of the body's cells to cysteinyl leukotrienes, which are chemical substances produced during the metabolism of arachidonic acid. These leukotrienes are released from various cells, including mast cells and eosinophils.

In conditions such as asthma and allergic rhinitis, the cysteinyl leukotrienes and their interaction with the leukotriene receptor play a role in the underlying pathophysiology. This includes the development of airway edema (swelling), smooth muscle contraction, and altered cellular activity associated with the inflammatory process. These processes contribute to the signs and symptoms of asthma, such as wheezing, shortness of breath, coughing, and allergic rhinitis symptoms.

By inhibiting the cysteinyl leukotriene receptor, XyfloTM helps to reduce the effects of cysteinyl leukotrienes on the body's cells, thereby alleviating airway constriction, inflammation, and other symptoms associated with asthma and allergic rhinitis.

Dosage & Administration of Xyflo 10mg Tablet

The recommended dosages for different age groups and indications for the medication are as follows:

Adults and adolescents (15 years and older):

• Asthma and Allergic Rhinitis: 10 mg per day
• Exercise-Induced Bronchoconstriction: 10 mg per day

Pediatric patients (6 to 14 years):

• Asthma and Allergic Rhinitis: 5 mg per day
• Exercise-Induced Bronchoconstriction: 5 mg per day

Pediatric patients (6 months to 5 years):

• Asthma and Allergic Rhinitis: 4 mg per day
• Exercise-Induced Bronchoconstriction: Not recommended

For patients with both asthma and allergic rhinitis, a single dose should be taken daily in the evening. This applies to all age groups mentioned above.

To prevent acute episodes of exercise-induced bronchoconstriction, a single dose should be taken at least 2 hours before engaging in exercise. However, exercise-induced bronchoconstriction is not recommended for pediatric patients aged 6 months to 5 years.

It is important to follow the prescribed dosage instructions provided by your healthcare professional for your specific condition. If you have any concerns or questions about the appropriate dosage or usage of the medication, it is advisable to consult your healthcare provider for further guidance.

Interaction

If you are allergic to Xyflo 10 or any of its contents, do not take them. If you have a mental problem, see your doctor before beginning Xyflo 10, as the medication might induce mood changes. (symptoms include anxiety, aggressive behavior, irritability, and restlessness). You may experience depression at times. Notify your doctor if you experience any of these symptoms. It is best to avoid coming into touch with recognized allergens (allergy-causing substances) such as pollen, dust, and so on. Certain foods have been linked to allergies.  Even if you are asymptomatic and feel OK, discontinuing Xyflo 10 abruptly may result in an acute asthma attack.

Contraindications

Xyflo 10 mg is contraindicated in patients who are hypersensitive to any component of this product.

Pregnancy & Lactation

There are no adequate and well-controlled studies on pregnant women. Xyflo 10 mg should be used during pregnancy only if clearly needed. Xyflo 10 mg is excreted in breast milk. So caution should be exercised when Montelukast is given to a nursing mother. 

Precautions & Warnings

• Xyflo 10 mg is not indicated for use in reversing bronchospasm in acute asthma attacks, including status asthmatics.
• Neuropsychiatric events include agitation, hostility, anxiousness, depression, disorientation, disturbance in attention, dream abnormalities, hallucinations, insomnia, irritability, memory impairment, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremors.
• Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose, and sneezing.

Storage Conditions

Store in a cool & dry place below 30°C, and protect from light & moisture. Keep out of reach of children.