Ticas 0.05% Cream 10gm

✔️ Uses of Ticas 0.05% Cream

• Allergic rhinitis
• Inflammatory skin conditions

✔️ How does Ticas 0.05% Cream work?

Ticas 0.05% Cream (Fluticasone propionate) works by inhibiting certain cells causing redness and swelling (mast cells, neutrophils, lymphocytes, and macrophages) as well as by blocking the release of chemicals causing allergic reactions (histamine). 

✔️ Side Effects of Ticas 0.05% Cream

• Dryness and irritation of the nose and throat
• Headache
• Nose bleed
• Allergic Skin Reaction
• Difficulty in breathing

✔️ Quick Suggestions:

• Apply a thin layer of the medicine to the affected area as instructed by your doctor.
• Follow all the usage instructions mentioned on the label or the package insert.
• Do not apply in larger or smaller quantities than recommended.
• Do not cover the application area with bandages or other coverings unless specifically instructed by your doctor.
• Contact your doctor if symptoms do not improve or resolve after 2 weeks of use.

✔️ Indication of Ticas 0.05% Cream

Ticas is used to relieve the symptoms of inflammation and itching associated with corticosteroid-responsive eczema or dermatitis.
Use as directed by a registered physician.

✔️ Pharmacology

Fluticasone propionate is a glucocorticoid that has strong topical anti-inflammatory properties with minimal HPA-axis suppression when applied to the skin. Its therapeutic index is higher than that of most other available steroids. Fluticasone propionate binds selectively to glucocorticoid receptors, which are thought to mediate the anti-inflammatory effects of corticosteroids. Studies show that it has a strong affinity for glucocorticoid receptors, a weak affinity for progesterone receptors, and virtually no affinity for mineralocorticoid, estrogen, or androgen receptors. The duration of the therapeutic effect is linked to the half-life of the fluticasone-glucocorticoid receptor complex, which is around 10 hours.

✔️ Dosage & Administration

Apply a thin layer to the affected area of the skin once daily.

✔️ Interaction

Ticas may interact with anti-fungal (ketoconazole) and HIV medications (ritonavir). Inform your doctor if you are taking any other steroid medicines.

Inform your doctor if you have hyperadrenocorticism, infections, ocular herpes simplex, glaucoma, cataracts, bone problems, chickenpox, measles, or tuberculosis.

✔️ Ticas is contraindicated in patients with the following conditions:

• Rosacea
• Acne vulgaris
• Perioral dermatitis
• Primary viral skin infections (e.g., herpes simplex, chickenpox)
• Hypersensitivity to any ingredients
• Perianal and genital itching
• Fungal or bacterial infections as the primary cause of skin lesions
• Dermatoses in children under one year of age, including diaper dermatitis

✔️ Pregnancy & Lactation

Fluticasone propionate should only be used during pregnancy if the potential benefit to the mother outweighs the possible risk to the fetus. It is unknown whether fluticasone is excreted in breast milk, but given the low likelihood of systemic absorption at recommended doses, the risks to a nursing infant are considered low. The potential benefits should be weighed against potential risks when used by breastfeeding mothers.

✔️ Precautions & Warnings

Although Ticas has a low risk of systemic absorption, prolonged use of large amounts over a large skin surface area—especially in infants and small children—could lead to adrenal suppression. Children are more susceptible to systemic toxicity because they absorb higher amounts of topical corticosteroids. Prolonged use on the face can cause skin thinning, so this should be taken into account when treating severe eczema. Infected inflammatory lesions require antimicrobial treatment, and corticosteroids should be discontinued if the infection spreads. Occlusive dressings may promote bacterial growth, so the skin should be cleansed before applying a fresh dressing.

✔️ Storage:

Store below 30°C. Do not freeze. Keep out of reach of children.