Rupita belongs to the category of non-sedating antihistamines. Rupita is indicated for the symptomatic treatment of Seasonal & Perennial Allergic Rhinitis and Urticaria.
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Rupatadine belongs to a class of drugs known as antihistamines or anti-allergics, utilized in treating allergic conditions like allergic rhinitis and urticaria. Allergic rhinitis, commonly referred to as hay fever, manifests as inflammation in the nose due to an exaggerated immune response to airborne allergens. Urticaria, also called hives, presents as sudden outbreaks of swollen, pale red bumps or plaques (wheals) on the skin, triggered either by the body's reaction to specific allergens or for unknown reasons.
The active ingredient in Rupatadine is rupatadine. It operates by diminishing the levels of histamine, a chemical substance responsible for instigating allergic symptoms such as itching, sneezing, runny nose, swelling, and rashes.
Rupatadine can be taken with or without food, swallowed whole with a glass of water, and should not be chewed, bitten, or broken. The frequency of tablet intake is determined by your medical condition, as advised by your doctor. While using Rupatadine, you may encounter common side effects like headaches, dizziness, dry mouth, fatigue, tiredness, nausea, and abdominal pain. Typically, these side effects diminish over time and do not necessitate medical intervention. However, if they persist, discontinuing the medication and consulting your doctor is recommended.
Avoid taking Rupatadine if you are allergic to rupatadine. Always adhere to your doctor's instructions regarding Rupatadine usage. Inform your doctor about any other medications you are taking alongside Rupatadine. Additionally, consult your doctor before using Rupatadine if you are pregnant, planning to conceive, or breastfeeding. Exercise caution when administering Rupatadine to elderly patients (aged > 65 years) due to an elevated risk of severe adverse effects. Similarly, patients with heart, kidney, or liver conditions should use Rupatadine cautiously.
Avoid consuming alcohol while undergoing treatment with this medication, as it may heighten the risk of severe adverse effects.
Rupita 10mg Tablet should not be used by pregnant women. Discuss all potential risks and benefits with your doctor before initiating treatment with this medication.
Breastfeeding women should refrain from using Rupatadine. Consult your doctor to weigh the risks and benefits, and follow their guidance regarding the continuation of medication or breastfeeding based on your clinical condition.
Some patients may experience drowsiness or dizziness while taking Rupita 10mg Tablet. Refrain from activities such as driving or operating machinery if you experience these symptoms during treatment.
Patients with a history of renal diseases should avoid using Rupatadine, as its safety and efficacy have not been clinically established in this population.
Rupatadine is not recommended for individuals with a history of renal diseases, as its safety and efficacy have not been clinically established in such patients.
Allergic-rhinitis and urticaria.
Rupatadine works by blocking the effects of histamine (chemical messenger) which causes allergic reactions, thereby providing relief from allergic symptoms such as swelling, itching, running nose, sneezing, rashes, and watery eyes.
Rupatadine is used to relieve the symptoms of allergic rhinitis such as sneezing, runny nose, and itching in the eyes and nose which is also used to relieve the symptoms associated with urticaria (an allergic skin rash) such as itching and hives (localized skin redness and swelling).
Rupatadine acts as a long-acting antagonist of histamine H1-receptors and platelet-activating factor (PAF). These substances contribute to bronchoconstriction and increased vascular permeability in inflammatory processes. By targeting both histamine and PAF, Rupatadine provides enhanced therapeutic effects compared to single-action antihistamines. It also inhibits mast cell degranulation triggered by various stimuli and suppresses the release of cytokines, including tumor necrosis factor-alpha (TNF α), in human mastocytes and monocytes.
Use cautiously; no dose adjustment is currently indicated.
Safety and efficacy have not been established in patients under 12 years of age.
Not recommended due to lack of relevant clinical data.
The most common adverse reaction in cases of overdose is drowsiness. In the event of accidental ingestion of very high doses, provide symptomatic treatment and supportive measures.
Avoid Rupatadine in individuals with hypersensitivity to Rupatadine or any excipients.
Clinical data on Rupatadine's effects during pregnancy are lacking. Pregnant women should avoid using Rupatadine unless the potential benefits outweigh the risks. Its excretion in breast milk is uncertain, so it's generally not recommended during lactation unless the benefits outweigh the risks.
Exercise caution in patients with known QT interval prolongation, uncorrected hypokalemia, or ongoing proarrhythmic conditions. Use with care in elderly patients (65 years and older). Currently, there's limited clinical experience in patients with impaired kidney or liver function, so the use of Rupita 10 mg tablets is not recommended in these cases.
Store below 30°C in a cool, dry place, away from light and moisture. Keep out of reach of children.
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